Acute Undifferentiated Leukaemia (AUL): diagnosis
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To diagnose acute undifferentiated leukaemia the cells need to meet specific criteria, and possible alternatives should be excluded. These are given in the table below:
Requirement 1
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No lineage can be assigned by lineage-defining markers of myeloid, B-lymphoid or T-lymphoid lineage
Review Criteria:
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Requirement 2
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Ensure that other conditions that may resemble undifferentiated acute leukaemia are excluded: particularly consider whether marker patterns suggest any of the following:
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Requirement 3
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Consider whether the case may be better described as Acute Leukaemia of Ambiguous Lineage - not otherwise specified (ALAL-NOS) - see guidance
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