Flow cytometry:AUL
From haematologyetc.co.uk
| Acute Undifferentiated Leukaemia (AUL): diagnosis |
To diagnose acute undifferentiated leukaemia the cells need to meet specific criteria, and possible alternatives should be excluded. These are given in the table below:
| Requirement 1 | |
| It is not possible to definitely assign any lineage using accepted criteria Myeloid lineage cannot be assigned (review criteria) Lineage defining B-lymphoid markers should not be expressed Review criteria for B-lymphoid lineage assgnment Lineage defining T-lymphoid markers should not be expressed Review criteria for T-lymphoid lineage assgnment | |
| Requirement 2 | |
| Ensure that other conditions that may resemble undifferentiated acute leukaemia are excluded: particularly consider whether marker patterns suggest any of the following: | |
| Requirement 3 | |
| Consider whether the case may be better described as Acute Leukaemia of Ambiguous Lineage - not otherwise specified (ALAL-NOS) - see guidance |