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Flow cytometry:AUL: Difference between revisions

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*[[Flow Cytometry:T-Lymphoid lineage assignment|T-Lymphoid]]
*[[Flow Cytometry:T-Lymphoid lineage assignment|T-Lymphoid]]
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|colspan="2" style = "font-size:90%; color:black; background:#ddeee1" |'''Requirement 2'''
|colspan="2" style = "font-size:90%; color:black; background:LightBlue" |'''Requirement 2'''
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|colspan="2" style = "font-size:90%; color:black;"|Ensure that other conditions that may resemble undifferentiated acute leukaemia are excluded: particularly consider whether marker patterns suggest any of the following:
|colspan="2" style = "font-size:90%; color:black;"|Ensure that other conditions that may resemble undifferentiated acute leukaemia are excluded: particularly consider whether marker patterns suggest any of the following:
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*[[Plasma cell leukaemia]]
*[[Plasma cell leukaemia]]
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|colspan="2" style = "font-size:90%; color:black; background:#ddeee1" |'''Requirement 3'''
|colspan="2" style = "font-size:90%; color:black; background:LightBlue" |'''Requirement 3'''
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|colspan="2" style = "font-size:90%; color:black;"|Consider whether the case may be better described as Acute Leukaemia of Ambiguous Lineage - not otherwise specified (ALAL-NOS) - see guidance
|colspan="2" style = "font-size:90%; color:black;"|Consider whether the case may be better described as Acute Leukaemia of Ambiguous Lineage - not otherwise specified (ALAL-NOS) - see guidance

Revision as of 00:53, 18 January 2024



Acute Undifferentiated Leukaemia (AUL): diagnosis


To diagnose acute undifferentiated leukaemia the cells need to meet specific criteria, and possible alternatives should be excluded. These are given in the table below:

Requirement 1
No lineage can be assigned by lineage-defining markers of myeloid, B-lymphoid or T-lymphoid lineage

Review Criteria:

Requirement 2
Ensure that other conditions that may resemble undifferentiated acute leukaemia are excluded: particularly consider whether marker patterns suggest any of the following:
Requirement 3
Consider whether the case may be better described as Acute Leukaemia of Ambiguous Lineage - not otherwise specified (ALAL-NOS) - see guidance