CD65: Difference between revisions
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:<span style="color:navy">'''Summary'''</span> | :<span style="color:navy">'''Summary'''</span> | ||
: | :CD65 supports the identification of acute myeloid leukaemia with granulocytic maturation and may be used to support the identification of myeloid differentiation in mixed phenotype acute leukaemia MPAL | ||
</div> | </div> | ||
:<span style="color:navy">'''Diagnostic Use'''</span> | :<span style="color:navy">'''Diagnostic Use'''</span> | ||
* | *This carbohydrate antigen has very simILar reactivity to CD15 and is expressed on the surface of maturing myeloid cells with highest expression on granulocytes and weaker expression on monocytes | ||
*CD65 is expressed on acute myeloid leukaemias with granulocytic maturation | |||
*During normal myelopoiesis the expression of CD65 follows the disappearance of the progenitor antigen CD33 | |||
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Latest revision as of 15:26, 14 June 2023
- Summary
- CD65 supports the identification of acute myeloid leukaemia with granulocytic maturation and may be used to support the identification of myeloid differentiation in mixed phenotype acute leukaemia MPAL
- Diagnostic Use
- This carbohydrate antigen has very simILar reactivity to CD15 and is expressed on the surface of maturing myeloid cells with highest expression on granulocytes and weaker expression on monocytes
- CD65 is expressed on acute myeloid leukaemias with granulocytic maturation
- During normal myelopoiesis the expression of CD65 follows the disappearance of the progenitor antigen CD33