Actions

Special

All public logs

Combined display of all available logs of haematologyetc.co.uk. You can narrow down the view by selecting a log type, the username (case-sensitive), or the affected page (also case-sensitive).

Logs
(newest | oldest) View ( | ) (20 | 50 | 100 | 250 | 500)
  • 21:05, 12 May 2023 John talk contribs created page CD23 (Created page with " <div style="background-color: #E0EEEE; {{round corners}} padding: 2em 2em; margin-right: 5px;"> :<span style="color:navy">'''Summary'''</span> :xxxx </div> <span style="color:navy">'''Normal expression and function'''</span> xxxxx <span style="color:navy">'''Diagnostic role'''</span> *xxxxx <span style="color:navy">'''Other relevant information:'''</span> xxxxx ---- <span style="color:navy">'''''SUMMARY TABLES'''''</span> <span style="font-...")
  • 20:32, 11 May 2023 John talk contribs created page CD4 & CD8 (Created page with " <div style="background-color: #E0EEEE; {{round corners}} padding: 2em 2em; margin-right: 5px;"> :'''Systemic disease:''' On T lymphocytes these two co-stimulatory molecules define different functional types; an altered ratio between CD4 and CD8 cells can indicate systemic disease or immune dysfunction :'''Neoplasia:''' Expanded populations of CD4 or CD8 cells (or T cells with unusual expression patterns of these molecules) may represent a malignant clone, and the CD4...")
  • 15:53, 10 May 2023 John talk contribs created page CD61 (Created page with " <div style="background-color: #E0EEEE; {{round corners}} padding: 2em 2em; margin-right: 5px;"> :<span style="color:navy">'''Summary'''</span> :xxxxx </div> :<span style="color:navy">'''Background'''</span> :xxxxxx :<span style="color:navy">'''Diagnostic Use'''</span> *xxxxx -----")
  • 15:53, 10 May 2023 John talk contribs created page CD43 (Created page with " <div style="background-color: #E0EEEE; {{round corners}} padding: 2em 2em; margin-right: 5px;"> :<span style="color:navy">'''Summary'''</span> :xxxxx </div> :<span style="color:navy">'''Background'''</span> :xxxxxx :<span style="color:navy">'''Diagnostic Use'''</span> *xxxxx -----")
  • 15:52, 10 May 2023 John talk contribs created page CD41 (Created page with " <div style="background-color: #E0EEEE; {{round corners}} padding: 2em 2em; margin-right: 5px;"> :<span style="color:navy">'''Summary'''</span> :xxxxx </div> :<span style="color:navy">'''Background'''</span> :xxxxxx :<span style="color:navy">'''Diagnostic Use'''</span> *xxxxx -----")
  • 12:43, 9 May 2023 John talk contribs created page CD22 (Created page with "CD22 expression is largely restricted to b cell lineage and expression is acquired at an early differentiation stage. *expression varies during mature b-cell development however the major value of CD22 lies in the identification of all based on high lineage-specificity and very early acquisition allowing the identification of pro-b all. normal expression and function CD22 is a membrane receptor that binds sialic acid containing glycans and expression is mostly rest...")
  • 23:16, 8 May 2023 John talk contribs created page CD1a (Created page with "A T cell marker that has value in specific circumstances Background CD1a is structurally related to major histocompatibility complex proteins and is thought to mediate the presentation of lipid and glycolipid antigens. CD1a expression is absent on very early thymocytes, but is acquired together with CD4 and CD8 as T cells develop in the thymus, then is lost in mature T cells. Diagnostic Use :A marker of early T-lineage :CD1A us useful in the identification of some cas...")
  • 21:58, 8 May 2023 John talk contribs created page CD19 (Created page with " <div style="background-color: #E0EEEE; {{round corners}} padding: 2em 2em; margin-right: 5px;"> :<span style="color:navy">'''Summary'''</span> :xxxx </div> <span style="color:navy">'''Normal expression and function'''</span> xxxxx <span style="color:navy">'''Diagnostic role'''</span> *xxxxx <span style="color:navy">'''Other relevant information:'''</span> xxxxx ---- <span style="color:navy">'''''SUMMARY TABLES'''''</span> <span style="font-...")
  • 13:23, 7 May 2023 John talk contribs created page CD10 (Created page with " <div style="background-color: #E0EEEE; {{round corners}} padding: 2em 2em; margin-right: 5px;"> :<span style="color:navy">'''Summary'''</span> :CD10 is expressed early pre-B ALL ("common ALL"), but also has wide expression on all subtypes notably also being expressed by Burkitt lymphoma and many cases of T-ALL :CD10 is also found on normal developing B-lymphocytes (haematogones) so is found very frequently in regenerating marrows :In mature lymphoproliferative...")
  • 14:13, 6 May 2023 John talk contribs created page CD2 (Created page with " <div style="background-color: #E0EEEE; {{round corners}} padding: 2em 2em; margin-right: 5px;"> :<span style="color:navy">'''Summary'''</span> :CD2 is a pan t-cell marker. In diagnostic use it may be less reliable than CD3 for identification of T-cell lineage, since loss of CD2 expression is seen in some peripheral T-cell lymphomas, and aberrant expression in AML is recognised (particularly the APL subtype). </div> <span style="color:navy">'''Normal expressi...")
  • 12:44, 6 May 2023 John talk contribs created page Extra (Created page with "CD14 aids recognition of bacteria by cells of monocytic lineage. it may generally be regarded as a pan-monocyte antigen when expressed in aml CD14 is a marker of monocytic lineage absence of CD14 expression does not preclude monocytic lineage since some typical monoblasts do not express this marker CD14 is not restricted to malignant cells and will be expressed by reactive monocytes and also by neoplastic cells of cmml normal expression and function together...")
  • 11:59, 6 May 2023 John talk contribs created page CD14 (Created page with "(259, 'cd14', ' cd14 aids recognition ofu800 bacteria byu800 cells ofu800 monocytic lineage. itu800 mayu800 generally beu800 regarded asu800 au800 panu800-monocyte antigen * when expressed inu800 amlu800 cd14 isu800 au800 marker ofu800 monocytic lineage * absence ofu800 cd14 expression does notu800 preclude monocytic lineage since some typical monoblasts dou800 notu800 express this marker * cd14 isu800 notu800 restricted tou800 malignant cells andu800 will beu800 express...")
  • 22:57, 3 May 2023 John talk contribs created page CD79a (Created page with "<span style="color:navy">'''''DETAILS'''''</span> CD38 helps mobilise intracellular calcium to activate a wide array of cell functions. In haematological cell types CD38 it is widely expressed by lymphoid cells )B, T and NK) as well as myeloid precursor cells and mature myeloid cells. It has particular diagnostic importance for lymphocytes where CD38 expression is acquired as stem cells commit to B-cell lineage, then is lost as mature B cells emerge from bone marrow be...")
  • 14:10, 3 May 2023 John talk contribs created page Key to marker expression table (Created page with " <span style="font-size:80%">'''''1. Colour key:''''' ''- the likelihood of any individual case expressing this marker, indicated by colour:'' </span> {| class=wikitable style="text-align: left; font-size:80%; width: 60%; height: 30px; |style= "width: 16.6%; background: #FFE4E1; |Few reported studies (though likely rare) |} {| class=wikitable style="text-align: left; font-size:80%; width:60%; height: 30px; |style= "width: 16.6%; background: #E6FAFF; |Expression may b...")
  • 15:28, 1 May 2023 John talk contribs created page CD4 (Created page with " <div style="background-color: #E0EEEE; {{round corners}} padding: 2em 2em; margin-right: 5px;"> :'''Systemic disease:''' On T lymphocytes these two co-stimulatory molecules define different functional types; an altered ratio between CD4 and CD8 cells can indicate systemic disease or immune dysfunction :'''Neoplasia:''' Expanded populations of CD4 or CD8 cells (or T cells with unusual expression patterns of these molecules) may represent a malignant clone, and the CD4...")
  • 10:21, 1 May 2023 John talk contribs created page CD11c (Created page with " <div style="background-color: #E0EEEE; {{round corners}} padding: 2em 2em; margin-right: 5px;"> :<span style="color:navy">'''Summary'''</span> :xxxx </div> <span style="color:navy">'''Normal expression and function'''</span> xxxxx <span style="color:navy">'''Diagnostic role'''</span> *xxxxx <span style="color:navy">'''Other relevant information:'''</span> xxxxx ---- <span style="color:navy">'''''SUMMARY TABLES'''''</span>")
  • 20:51, 30 April 2023 John talk contribs created page CD3 (Created page with " <div style="background-color: #E0EEEE; {{round corners}} padding: 2em 2em; margin-right: 5px;"> :<span style="color:navy">'''Summary'''</span> :xxxx </div> <span style="color:navy">'''Normal expression and function'''</span> xxxxx <span style="color:navy">'''Diagnostic role'''</span> *xxxxx <span style="color:navy">'''Other relevant information:'''</span> xxxxx ---- <span style="color:navy">'''''SUMMARY TABLES'''''</span>")
  • 17:10, 30 April 2023 John talk contribs created page CD5 (Created page with " <div style="background-color: #E0EEEE; {{round corners}} padding: 2em 2em; margin-right: 5px;"> :<span style="color:navy">'''Summary'''</span> :'''For mature B cell neoplasms''': CD5 is used to indicate likely CLL or MCL. However, expression is present on a subset of normal B cells, and also less frequently on other lymphoma types. Full interpretation therefore requires consideration of clonality and other markers. :'''In acute lymphoblastic leukaemia''': CD5 is u...")
  • 10:24, 30 April 2023 John talk contribs created page CD45 (Created page with "<span style="color:navy">'''''SUMMARY TABLES'''''</span> {| class=wikitable style="text-align: center; font-size:80%; width: 100%; height 20px;" |- !colspan="7"|<span style="font-size:100%">'''CD13 expression: primitive cell types'''</font> |- ! AML !! B ALL !! Burkitt || T ALL !! ETP ALL ('''i''') !! MPAL '''i || Hgns '''i''' |- |style="width: 14.25%; background: #FFE4E1 #FFE4E1 #66e0ff #00b8e6 #006699; color:white"|Limited Rare Possible...")
  • 13:46, 26 April 2023 John talk contribs created page CD38 (Created page with " <span style="color:navy">'''''DETAILS'''''</span> CD38 helps initiate the mobilsation of intracellular calcium, activating a wide array of cell functions that depend on cell type. In haematological cell types CD38 is widely expressed by lymphoid cells and by particular myeloid cells – often in a stage-specific manner. For B lymphocytes CD38 expression is acquired as stem cells commit to B-cell lineage, then lost as mature B cells emerge from bone marrow before be...")
  • 12:50, 26 April 2023 John talk contribs created page CD13 (Created page with " <div style="background-color: #E0EEEE; {{round corners}} padding: 2em 2em; margin-right: 5px;"> *The principle diagnostic value of CD38 is that its expression is retained and generally increased during differentiation to plasma cells *CD38 expression has some value in predicting prognosis in CLL *CD38 is also expressed by committed stem cells together with CD34 and can occasionally be of value in acute leukaemia diagnosis </div> <span style="color:navy">'''Norma...")
  • 12:36, 26 April 2023 John talk contribs created page Flow Cytometry (Created page with " <span style="color:navy>1. ''Markers used mainly for gating:''</span> {|style="width: 80px; height: 80px; text-align:center; font-style: bold; font-size: 120%; color: teal; background: #ededed; border-style: solid; border-width: 2px" | <span style="color:teal">'''CD45'''</span> |} ---- <span style="color:navy>2. ''Non CD-classified markers''</span> {|style="float:left; width: 80px; height: 80px; text-align:center; font-style: bold; color: maroon; back...")
  • 16:50, 23 April 2023 John talk contribs created page Ex-flagellation (Created page with "<span style="color:navy>'''Description'''</span> The male and female gametocytes of the malarial parasite may continue to mature in stored blood, in particular the pH change and temperature change may resemble changes normally encountered in the mosquito stomach, where the male gametocyte releases the microgametes as part of sexual replication. This process can be detected in some stored cases. ---- Early trophozoites: <gallery mode="nolines" widths="220px" heights...")
  • 16:27, 23 April 2023 John talk contribs created page Ring forms (Created page with " ---- '''What is a ring form''' <gallery mode="nolines" widths="220px" heights="220px" > File:Ring_cartoon.jpg|link={{filepath:|MFETr.jpg}} </gallery> The earliest stage following red cell invasion has a typical ting form: *a = chromatin dot *b = digestive vacuole *c = parasite cytoplasm ---- <span style="color:navy>'''Description'''</span> At the earliest stage of red cell infection parasites have a ring form and distinction between species may not be easy (or ev...")
  • 16:10, 23 April 2023 John talk contribs created page Distrorted erythrocyte shape (Created page with " ---- <gallery mode="nolines" widths="220px" heights="220px" > File:MDi1.jpg|: ''P.vivax''|link={{filepath:MDi1.jpg}} </gallery> <span style="color:navy>'''Description'''</span> Distortion of the erythrocyte shape is one of the modifications caused by parasite invasion. The most substantial distortion is caused by ''P.vivax'' in which the red cells become both enlarged and irregular in shape. <span style="color:navy>'''Species significance'''</span> Marked red...")
  • 16:08, 23 April 2023 John talk contribs created page Phagocytosed malaria pigment (Created page with " ---- '''Appearance:''' In the context of malarial infection the neutrophils may contain masses of phagocytosed brown or golden malaria pigment within their cytoplasm. ---- '''Images of malaria pigment''' <gallery mode="nolines" widths="270px" heights="300px" > File:Mp1.jpg|link= File:Mp2.jpg|link= File:Mp3.jpg|link= </gallery> <span style="font-size:85%"> ''Images of neutrophils containing malaria pigment: Image 1 shows a schizont in the process of releasing daug...")
  • 16:06, 23 April 2023 John talk contribs created page Malaria pigment (Created page with " ---- <gallery mode="nolines" widths="220px" heights="220px" > File:MPi1.jpg|: ''P.malariae'' with golden pigment over the parasite surface|link={{filepath:MPi1.jpg}} </gallery> <span style="color:navy>'''Description'''</span> During their development malarial parasites metabolise the haemoglobin within erythrocytes to support their growth - hence infected cells become "ghost cells" devoid of visible haemoglobin at later stages of parasite development. As part of th...")
  • 16:01, 23 April 2023 John talk contribs created page Schüffner's dots (Created page with " ---- <gallery mode="nolines" widths="220px" heights="220px" > File:MSc1.jpg|link={{filepath:MSc1.jpg}} File:MSc2.jpg|link={{filepath:MSc2.jpg}} File:MSc3.jpg|link={{filepath:MSc3.jpg}} File:MSc4.jpg|link={{filepath:MSc4.jpg}} </gallery> Different intensities of cytoplasmic dots, from faint to intense during the development of ''P.vivax''. Note that even when faint the number of dots is high (compare with the Maurer's dots and clefts of ''P.falciparum'') <span style...")
  • 15:58, 23 April 2023 John talk contribs created page Band appearance (Created page with " ---- <gallery mode="nolines" widths="220px" heights="220px" > File:MBa3.jpg|: ''P.malarae'' mature band|link={{filepath:MBa3.jpg}} File:Mba3.jpg|: ''P.malarae'' early band|link={{filepath:MBa3.jpg}} File:MBa2.jpg|: ''P.malarae'' mature band|link={{filepath:MBa2.jpg}} </gallery> <span style="color:navy>'''Description'''</span> An early or late trophozoite form that is very elongated and extends close to, or entirely across, the diameter of the erythocyte <span s...")
  • 14:30, 23 April 2023 John talk contribs created page Banana gametocyte (Created page with " ---- <gallery mode="nolines" widths="220px" heights="220px" > File:MB1.jpg|: ''P.falciparum'' macrogametocyte|link={{filepath:MB1.jpg}} File:MB2.jpg|: ''P.falciparum microgametocyte''|link={{filepath:MB2.jpg}} </gallery> <span style="color:navy>'''Description'''</span> The gametocyte stage of ''P.falciparum'' has the form of a round-ended rod. The rod is slightly longer than a red cell so becomes curved by the red cell membrane and is often described a "banana shap...")
  • 14:29, 23 April 2023 John talk contribs created page Amoeboid forms (Created page with " ---- <gallery mode="nolines" widths="220px" heights="220px" > File:MAm2.jpg|: ''P.vivax''|link={{filepath:MAm2.jpg}} </gallery> <span style="color:navy>'''Description'''</span> The late trophozoite of ''P.vivax'' becomes more solid, but with an irregular form that is said to resemble an amoeba with extended processes. Other features of the species will also be detected. <span style="color:navy>'''Species significance'''</span> A fairly specific feature of ''P...")
  • 14:19, 23 April 2023 John talk contribs created page Forms Main Menu (Created page with "---- <gallery mode="nolines" widths="300px" heights="260px" > File:Blood_stages_1.jpg|link={{filepath:MAm3.jpg}} </gallery> '''INDEX''' ---- '''A''' Accolé form - the "edge" parasite, most closely associated with ''P.falcparum'' though certainly not restricted to this species Amoeboid forms - a particular description applied to the irregular solid late trophozoites from ''P.vivax'', very typical of the species Angular forms - a solid late trophoz...")
  • 14:17, 23 April 2023 John talk contribs created page Species Main Menu (Created page with " ---- '''''Plasmodium falciparum''''' right|400px|link= '''Brief Summary''' *Small fine ring forms with certain characteristic features *Rings have relatively uniform appearance *Maurer's dots and clefts in late trophozoites *Schizonts very rarely seen *Characteristic elongated (often curved) 'banana' gametocyes '''More''' click for full description click for gallery of forms ----...")
  • 14:12, 23 April 2023 John talk contribs created page Malaria Index (Created page with " ---- '''''Plasmodium falciparum''''' right|400px|link= '''Brief Summary''' *Small fine ring forms with certain characteristic features *Rings have relatively uniform appearance *Maurer's dots and clefts in late trophozoites *Schizonts very rarely seen *Characteristic elongated (often curved) 'banana' gametocyes '''More''' click for full description click for gallery of forms ----...")
  • 13:36, 29 March 2023 John talk contribs uploaded File:RedCellsBack.png
  • 13:36, 29 March 2023 John talk contribs created page File:RedCellsBack.png
  • 13:32, 29 March 2023 John talk contribs created page Main Page/new (Created page with " ------ <span style="color: navy> '''Thank you for visiting HaematologyETC''' </span> we are now getting fixed slowly! <gallery mode="nolines" widths="240px" heights="240px" border="1px" > File:getting_fixed.jpg|link={{filepath:getting_fixed.jpg}}}} </gallery> We are uploading the original pages and hope to have some working content soon! Please re-visit for updates, Thanks for visiting '''John Burthem''' and '''Michelle Brereton''' ------ ---- Red Cell Me...")
  • 22:10, 28 March 2023 John talk contribs created page Red Cell Menu (Created page with " ------ <span style="color: navy> '''Thank you for visiting HaematologyETC''' </span> we are now getting fixed slowly! <gallery mode="nolines" widths="240px" heights="240px" border="1px" > File:getting_fixed.jpg|link={{filepath:getting_fixed.jpg}}}} </gallery> We are uploading the original pages and hope to have some working content soon! Please re-visit for updates, Thanks for visiting '''John Burthem''' and '''Michelle Brereton''' ------ ---- test te...")
  • 22:07, 28 March 2023 John talk contribs uploaded File:PH2A.jpg
  • 22:07, 28 March 2023 John talk contribs created page File:PH2A.jpg
  • 22:07, 28 March 2023 John talk contribs uploaded File:PH1A.png
  • 22:07, 28 March 2023 John talk contribs created page File:PH1A.png
  • 21:48, 28 March 2023 John talk contribs uploaded File:BS1A.png
  • 21:48, 28 March 2023 John talk contribs created page File:BS1A.png
  • 21:34, 28 March 2023 John talk contribs uploaded File:HJ2A.jpg
  • 21:34, 28 March 2023 John talk contribs created page File:HJ2A.jpg
  • 21:33, 28 March 2023 John talk contribs uploaded File:HJ1A.png
  • 21:33, 28 March 2023 John talk contribs created page File:HJ1A.png
  • 21:17, 28 March 2023 John talk contribs uploaded File:HJ0.png
  • 21:17, 28 March 2023 John talk contribs created page File:HJ0.png
(newest | oldest) View ( | ) (20 | 50 | 100 | 250 | 500)
Retrieved from ‘https://haematologyetc.co.uk/index.php?title=Special:Log’