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|colspan="1" style = "font-size:90%; color:black;" |'''CD23'''
|colspan="1" style = "font-size:90%; color:black;" |CD23
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|colspan="1" style = "font-size:90%; color:black;" |'''CD79b'''
|colspan="1" style = "font-size:90%; color:black;" |CD79b
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|colspan="1" style = "font-size:90%; color:black;" |'''CD200'''
|colspan="1" style = "font-size:90%; color:black;" |CD200
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|colspan="1" style = "font-size:90%; color:black;" |'''FMC7'''
|colspan="1" style = "font-size:90%; color:black;" |FMC7
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|colspan="1" style = "font-size:80%;"|May be expressed by atypical cases, generally absent
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!colspan="4" style = "font-size:90%; background:#DAE8F2"|Other relevant markers  
!colspan="4" style = "font-size:90%; background:#DAE8F2"|Other relevant markers  

Revision as of 13:49, 12 July 2023


DLBCL.jpg


Background to flow cytometric diagnosis

This is an uncommon diagnosis by flow cytometry as DLBCL cells generally circulate and involve bone marrow only at only a late stage in disease (ofetn when a diagnosis has already been made). However, occasionally these cases can present as a new diagnosis by blood or marrow and can be difficult as marker expression is often variable between cases.


Immunophenotype of DLBCL
Major markers useful in CLL diagnosis
Marker Freq Level Comment
CD19 -
κ/λ -
CD5 -
CD23 -
CD79b -
CD200 -
FMC7
Other relevant markers
CD10 -
CD11C -
CD20 -
CD25 -
CD38 -
CD43 -
CD103 -
CD138 -


Key to table:

Key to colour code for expression frequency Click for link

Key to expression strength code and use Click for link