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10:24, 30 April 2023 John talk contribs created page CD45 (Created page with "'''''SUMMARY TABLES''''' {| class=wikitable style="text-align: center; font-size:80%; width: 100%; height 20px;" |- !colspan="7"|'''CD13 expression: primitive cell types''' |- ! AML !! B ALL !! Burkitt || T ALL !! ETP ALL ('''i''') !! MPAL '''i || Hgns '''i''' |- |style="width: 14.25%; background: #FFE4E1 #FFE4E1 #66e0ff #00b8e6 #006699; color:white"|Limited Rare Possible...")
13:46, 26 April 2023 John talk contribs created page CD38 (Created page with " '''''DETAILS''''' CD38 helps initiate the mobilsation of intracellular calcium, activating a wide array of cell functions that depend on cell type. In haematological cell types CD38 is widely expressed by lymphoid cells and by particular myeloid cells – often in a stage-specific manner. For B lymphocytes CD38 expression is acquired as stem cells commit to B-cell lineage, then lost as mature B cells emerge from bone marrow before be...")
12:50, 26 April 2023 John talk contribs created page CD13 (Created page with " <div style="background-color: #E0EEEE; {{round corners}} padding: 2em 2em; margin-right: 5px;"> *The principle diagnostic value of CD38 is that its expression is retained and generally increased during differentiation to plasma cells *CD38 expression has some value in predicting prognosis in CLL *CD38 is also expressed by committed stem cells together with CD34 and can occasionally be of value in acute leukaemia diagnosis </div> '''Norma...")
12:36, 26 April 2023 John talk contribs created page Flow Cytometry (Created page with " 1. ''Markers used mainly for gating:'' {|style="width: 80px; height: 80px; text-align:center; font-style: bold; font-size: 120%; color: teal; background: #ededed; border-style: solid; border-width: 2px" | '''CD45''' |} ---- 2. ''Non CD-classified markers'' {|style="float:left; width: 80px; height: 80px; text-align:center; font-style: bold; color: maroon; back...")
16:50, 23 April 2023 John talk contribs created page Ex-flagellation (Created page with "'''Description''' The male and female gametocytes of the malarial parasite may continue to mature in stored blood, in particular the pH change and temperature change may resemble changes normally encountered in the mosquito stomach, where the male gametocyte releases the microgametes as part of sexual replication. This process can be detected in some stored cases. ---- Early trophozoites: <gallery mode="nolines" widths="220px" heights...")
16:27, 23 April 2023 John talk contribs created page Ring forms (Created page with " ---- '''What is a ring form''' <gallery mode="nolines" widths="220px" heights="220px" > File:Ring_cartoon.jpg|link={{filepath:|MFETr.jpg}} </gallery> The earliest stage following red cell invasion has a typical ting form: *a = chromatin dot *b = digestive vacuole *c = parasite cytoplasm ---- '''Description''' At the earliest stage of red cell infection parasites have a ring form and distinction between species may not be easy (or ev...")
16:10, 23 April 2023 John talk contribs created page Distrorted erythrocyte shape (Created page with " ---- <gallery mode="nolines" widths="220px" heights="220px" > File:MDi1.jpg|: ''P.vivax''|link={{filepath:MDi1.jpg}} </gallery> '''Description''' Distortion of the erythrocyte shape is one of the modifications caused by parasite invasion. The most substantial distortion is caused by ''P.vivax'' in which the red cells become both enlarged and irregular in shape. '''Species significance''' Marked red...")
16:08, 23 April 2023 John talk contribs created page Phagocytosed malaria pigment (Created page with " ---- '''Appearance:''' In the context of malarial infection the neutrophils may contain masses of phagocytosed brown or golden malaria pigment within their cytoplasm. ---- '''Images of malaria pigment''' <gallery mode="nolines" widths="270px" heights="300px" > File:Mp1.jpg|link= File:Mp2.jpg|link= File:Mp3.jpg|link= </gallery> ''Images of neutrophils containing malaria pigment: Image 1 shows a schizont in the process of releasing daug...")
16:06, 23 April 2023 John talk contribs created page Malaria pigment (Created page with " ---- <gallery mode="nolines" widths="220px" heights="220px" > File:MPi1.jpg|: ''P.malariae'' with golden pigment over the parasite surface|link={{filepath:MPi1.jpg}} </gallery> '''Description''' During their development malarial parasites metabolise the haemoglobin within erythrocytes to support their growth - hence infected cells become "ghost cells" devoid of visible haemoglobin at later stages of parasite development. As part of th...")
16:01, 23 April 2023 John talk contribs created page Schüffner's dots (Created page with " ---- <gallery mode="nolines" widths="220px" heights="220px" > File:MSc1.jpg|link={{filepath:MSc1.jpg}} File:MSc2.jpg|link={{filepath:MSc2.jpg}} File:MSc3.jpg|link={{filepath:MSc3.jpg}} File:MSc4.jpg|link={{filepath:MSc4.jpg}} </gallery> Different intensities of cytoplasmic dots, from faint to intense during the development of ''P.vivax''. Note that even when faint the number of dots is high (compare with the Maurer's dots and clefts of ''P.falciparum'') <span style...")
15:58, 23 April 2023 John talk contribs created page Band appearance (Created page with " ---- <gallery mode="nolines" widths="220px" heights="220px" > File:MBa3.jpg|: ''P.malarae'' mature band|link={{filepath:MBa3.jpg}} File:Mba3.jpg|: ''P.malarae'' early band|link={{filepath:MBa3.jpg}} File:MBa2.jpg|: ''P.malarae'' mature band|link={{filepath:MBa2.jpg}} </gallery> '''Description''' An early or late trophozoite form that is very elongated and extends close to, or entirely across, the diameter of the erythocyte <span s...")
14:30, 23 April 2023 John talk contribs created page Banana gametocyte (Created page with " ---- <gallery mode="nolines" widths="220px" heights="220px" > File:MB1.jpg|: ''P.falciparum'' macrogametocyte|link={{filepath:MB1.jpg}} File:MB2.jpg|: ''P.falciparum microgametocyte''|link={{filepath:MB2.jpg}} </gallery> '''Description''' The gametocyte stage of ''P.falciparum'' has the form of a round-ended rod. The rod is slightly longer than a red cell so becomes curved by the red cell membrane and is often described a "banana shap...")
14:29, 23 April 2023 John talk contribs created page Amoeboid forms (Created page with " ---- <gallery mode="nolines" widths="220px" heights="220px" > File:MAm2.jpg|: ''P.vivax''|link={{filepath:MAm2.jpg}} </gallery> '''Description''' The late trophozoite of ''P.vivax'' becomes more solid, but with an irregular form that is said to resemble an amoeba with extended processes. Other features of the species will also be detected. '''Species significance''' A fairly specific feature of ''P...")
14:19, 23 April 2023 John talk contribs created page Forms Main Menu (Created page with "---- <gallery mode="nolines" widths="300px" heights="260px" > File:Blood_stages_1.jpg|link={{filepath:MAm3.jpg}} </gallery> '''INDEX''' ---- '''A''' Accolé form - the "edge" parasite, most closely associated with ''P.falcparum'' though certainly not restricted to this species Amoeboid forms - a particular description applied to the irregular solid late trophozoites from ''P.vivax'', very typical of the species Angular forms - a solid late trophoz...")
14:17, 23 April 2023 John talk contribs created page Species Main Menu (Created page with " ---- '''''Plasmodium falciparum''''' right|400px|link= '''Brief Summary''' *Small fine ring forms with certain characteristic features *Rings have relatively uniform appearance *Maurer's dots and clefts in late trophozoites *Schizonts very rarely seen *Characteristic elongated (often curved) 'banana' gametocyes '''More''' click for full description click for gallery of forms ----...")
14:12, 23 April 2023 John talk contribs created page Malaria Index (Created page with " ---- '''''Plasmodium falciparum''''' right|400px|link= '''Brief Summary''' *Small fine ring forms with certain characteristic features *Rings have relatively uniform appearance *Maurer's dots and clefts in late trophozoites *Schizonts very rarely seen *Characteristic elongated (often curved) 'banana' gametocyes '''More''' click for full description click for gallery of forms ----...")
13:36, 29 March 2023 John talk contribs uploaded File:RedCellsBack.png
13:36, 29 March 2023 John talk contribs created page File:RedCellsBack.png
13:32, 29 March 2023 John talk contribs created page Main Page/new (Created page with " ------ '''Thank you for visiting HaematologyETC''' we are now getting fixed slowly! <gallery mode="nolines" widths="240px" heights="240px" border="1px" > File:getting_fixed.jpg|link={{filepath:getting_fixed.jpg}}}} </gallery> We are uploading the original pages and hope to have some working content soon! Please re-visit for updates, Thanks for visiting '''John Burthem''' and '''Michelle Brereton''' ------ ---- Red Cell Me...")
22:10, 28 March 2023 John talk contribs created page Red Cell Menu (Created page with " ------ '''Thank you for visiting HaematologyETC''' we are now getting fixed slowly! <gallery mode="nolines" widths="240px" heights="240px" border="1px" > File:getting_fixed.jpg|link={{filepath:getting_fixed.jpg}}}} </gallery> We are uploading the original pages and hope to have some working content soon! Please re-visit for updates, Thanks for visiting '''John Burthem''' and '''Michelle Brereton''' ------ ---- test te...")

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