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Schüffner's dots: Difference between revisions

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(Created page with " ---- <gallery mode="nolines" widths="220px" heights="220px" > File:MSc1.jpg|link={{filepath:MSc1.jpg}} File:MSc2.jpg|link={{filepath:MSc2.jpg}} File:MSc3.jpg|link={{filepath:MSc3.jpg}} File:MSc4.jpg|link={{filepath:MSc4.jpg}} </gallery> Different intensities of cytoplasmic dots, from faint to intense during the development of ''P.vivax''. Note that even when faint the number of dots is high (compare with the Maurer's dots and clefts of ''P.falciparum'') <span style...")
 
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|colspan="1" style = "font-size:100%; color:black; background: FFFAFA"|<span style="color:navy>'''What are Schüffner's dots?'''</span>
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Schüffner's dots are red-purple dots seen in ''P.vivax''. They are morphologically indistinguishable from the James' dots of ''P.ovale'' but are very diffrent from the more dense and blue coloured Maurer's dots and clefts of ''P.falciparum''. Like all parasite structures Schüffner's dots form progressively, and may not be seen in very early trophozoites.


Different intensities of cytoplasmic dots, from faint to intense during the development of ''P.vivax''. Note that even when faint the number of dots is high (compare with the Maurer's dots and clefts of ''P.falciparum'')


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<span style="color:navy>'''Description'''</span>
<span style="font-size:100%">Well formed Schüffner's dots in a trophozoite of ''P.vivax''; note that the dots are far too numerous to count and have a red/purple colour; remeber also that their appearance is highly dependent on the correct staining pH.</span>
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These are frequent red-purple dots in the erythrocyte cytoplasm of cells infected by ''P.vivax'' (like the James' dots seen in ''P.ovale'') that develop from early trophozoite infection as faint dots, then become more obvious in all mature forms. These represent modification of the red cell by the parasite''.
<span style="color:navy>'''Species significance'''</span> 


These dots are a feature of ''P.vivax'', but are morphologically indistinguishable from the James dots of ''P.ovale''. Distinction between these species must therefore be made based on other diagnostic crieria.




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<span style="color:navy>'''Species significance'''</span>
<span style="color:navy>'''Additional images'''</span>


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File:Schuf1.jpg|A|link={{filepath:Schuf1.jpg}}
File:Schuf3.jpg|B|link={{filepath:Schuf3.jpg}}
File:Schuf4.jpg|C|link={{filepath:Schuf4.jpg}}
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These dots are restricted to ''P.ovale'' (but are indistinguishable from the Schüffner's dots of ''P.vivax)''. Note the appearance of dots is highly dependent on correct staining pH.
<span style="font-size:100%">The appearance of Schüffner's dots during the develoment of ''P.vivax'' trophozites. These are shown from their earliest detectable form in an early trophozoite that has also begun to increase the size and distort the erythrocyte (A), these are more fully developed at later stages (B) and are highly visible in the amoeboid late trophozoite (C). </span>
 
 
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Latest revision as of 13:44, 3 April 2024


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What are Schüffner's dots?

Schüffner's dots are red-purple dots seen in P.vivax. They are morphologically indistinguishable from the James' dots of P.ovale but are very diffrent from the more dense and blue coloured Maurer's dots and clefts of P.falciparum. Like all parasite structures Schüffner's dots form progressively, and may not be seen in very early trophozoites.


Well formed Schüffner's dots in a trophozoite of P.vivax; note that the dots are far too numerous to count and have a red/purple colour; remeber also that their appearance is highly dependent on the correct staining pH.


Species significance

These dots are a feature of P.vivax, but are morphologically indistinguishable from the James dots of P.ovale. Distinction between these species must therefore be made based on other diagnostic crieria.



Additional images

The appearance of Schüffner's dots during the develoment of P.vivax trophozites. These are shown from their earliest detectable form in an early trophozoite that has also begun to increase the size and distort the erythrocyte (A), these are more fully developed at later stages (B) and are highly visible in the amoeboid late trophozoite (C).