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(Created page with " ---- '''What is a ring form''' <gallery mode="nolines" widths="220px" heights="220px" > File:Ring_cartoon.jpg|link={{filepath:|MFETr.jpg}} </gallery> The earliest stage following red cell invasion has a typical ting form: *a = chromatin dot *b = digestive vacuole *c = parasite cytoplasm ---- <span style="color:navy>'''Description'''</span> At the earliest stage of red cell infection parasites have a ring form and distinction between species may not be easy (or ev...")
 
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'''Navigation'''</br>
[[Plasmodium falciparum: Morphology|Go Back]]
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'''What is a ring form'''
{| class="wikitable" style="border-style: solid; border-width: 4px; color:black"
|colspan="1" style = "font-size:100%; color:black; background: FFFAFA"|<span style="color:navy>'''What is a ring form?'''</span>




<gallery mode="nolines" widths="220px" heights="220px" >
<gallery mode="nolines" widths="220px" heights="220px" >
File:Ring_cartoon.jpg|link={{filepath:|MFETr.jpg}}
File:Ring_c.jpg|link={{filepath:|Ring_c.jpg}}
File:MMETr.jpg|link={{filepath:|MMETr.jpg}}
</gallery>
</gallery>


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At the earliest stage of red cell infection parasites have a ring form and distinction between species may not be easy (or even possible); however, as the parasite mature and develop differences become more apparent. In some species the ring form is maintained until late stages of maturation, in others there is loss of a typical ring appearance
At the earliest stage of red cell infection parasites of all species have the form of a "ring". Distinction between species at this stage may not be easy (or even possible). However as the parasites mature and develop differences between species become more apparent. In some species the ring appearance is maintained until late stages of maturation, in others it is lost progressively as they mature.  
 
*''P.falciparum''  Typically small and delicate, these ring forms tend to persist from early trophozoite until late stages, during this time they may thicken
*''P.ovale'' Typically large and robust rings, but maintain a ring shape until late stages of development (contrast with ''P.vivax
*''P.malariae'' Small but more substantial that ''P.falciparum'', these parasites become more solid or bad like, losing the ring form as they develop
*''P.knowlesi'' Early forms resemble ''P.falciparum'', but as they mature they often extend and become solid or band-like resembling ''P.malariae
*''P.vivax'' Early stages appear as rings, but then become irregular and eventually the more typical amoeboid appearance appears
 
 
 
These changes are illustrated for early and late trophozoite below:
 
----
''P.falciparum''
 
 
<gallery mode="nolines" widths="220px" heights="220px" >
File:MFETr.jpg|link={{filepath:|MFETr.jpg}}
File:MFITr.jpg|link={{filepath:MFITr.jpg}}
File:MFLTr.jpg|link={{filepath:MFLTr.jpg}}
</gallery>
 
Small and often delicate rings at early stages, these thicken at later stages, although they remain relatively small with a "ring appearance"
 
----
''P.ovale''
 
<gallery mode="nolines" widths="220px" heights="220px" >
File:MOETr.jpg|link={{filepath:|MOETr.jpg}}
File:MOITr.jpg|link={{filepath:MOITr.jpg}}
File:MOLTr.jpg|link={{filepath:MOLTr.jpg}}
</gallery>
 
Robust rings that enlarge during parasite development, although the ring form can often still be distinguished
 
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''P.malariae''
 
 
<gallery mode="nolines" widths="220px" heights="220px" >
File:MMETr.jpg|link={{filepath:|MMETr.jpg}}
File:MMITr.jpg|link={{filepath:MMITr.jpg}}
File:MMLTr.jpg|link={{filepath:MMLTr.jpg}}
</gallery>
 
Small but more robust than ''P.falciparum'', the parasites become more solid as they develop and may extend as a band across the cells
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''P.knowlesi''


 
The different appearances of rings (or indeed their loss) can be very useful in identifying the different malaria species. For detailed illustration of maturing trophozoites [[Trophozoites: diagnostic guide|see this link]]:
<gallery mode="nolines" widths="220px" heights="220px" >
File:MKETr.jpg|small or normal ''P.malariae (round)|link={{filepath:|MKETr.jpg}}
File:MKITr.jpg|normal sized ''P.falciparum'' (round)|link={{filepath:MKITr.jpg}}
File:MKLTr.jpg|ormal or enlarged ''P.ovale'' (may become ovoid)|link={{filepath:MKLTr.jpg}}
</gallery>
 
 
----
''P.vivax''
 
 
<gallery mode="nolines" widths="220px" heights="220px" >
File:MVETr.jpg|small or normal ''P.malariae (round)|link={{filepath:|MVETr.jpg}}
File:MVITr.jpg|normal sized ''P.falciparum'' (round)|link={{filepath:MVITr.jpg}}
File:MVLTr.jpg|ormal or enlarged ''P.ovale'' (may become ovoid)|link={{filepath:MVLTr.jpg}}
</gallery>
 
 
 
----
 
 
<span style="color:navy>'''Species significance'''</span>
 
 
These changes can be very helpful in identifying malaria species
 
 
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Latest revision as of 22:04, 18 March 2024

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What is a ring form?


  • Ring c.jpg
  • MMETr.jpg

The earliest stage following red cell invasion has a typical ting form:

  • a = chromatin dot
  • b = digestive vacuole
  • c = parasite cytoplasm

Description


At the earliest stage of red cell infection parasites of all species have the form of a "ring". Distinction between species at this stage may not be easy (or even possible). However as the parasites mature and develop differences between species become more apparent. In some species the ring appearance is maintained until late stages of maturation, in others it is lost progressively as they mature.

The different appearances of rings (or indeed their loss) can be very useful in identifying the different malaria species. For detailed illustration of maturing trophozoites see this link:

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