CD7: Difference between revisions
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:<span style="color:navy">'''Background'''</span> | :<span style="color:navy">'''Background'''</span> | ||
:CD7 is a transmembrane protein that supports T cell interactions with B cells during lymphoid development. Expression is acquired during thymic development of T cells appearing before other | :CD7 is a transmembrane protein that supports T cell interactions with B cells during lymphoid development. Expression is acquired during thymic development of T cells appearing before other T-lineage markers, and expression is retained by mature T cells. | ||
Revision as of 15:11, 13 May 2023
- Summary
- CD7 is a pan T-cell marker that is useful for identifying T cells at very early stages of maturation. However, its value is limited by a high frequency of aberrant expression by other lineages that means caution is required in its interpretation
- In some mature T cell disorders variation of expression of CD7 can have diagnostic value
- Background
- CD7 is a transmembrane protein that supports T cell interactions with B cells during lymphoid development. Expression is acquired during thymic development of T cells appearing before other T-lineage markers, and expression is retained by mature T cells.
- Diagnostic Use
- xxxxx