CD7: Difference between revisions
From haematologyetc.co.uk
(Created page with " <div style="background-color: #E0EEEE; {{round corners}} padding: 2em 2em; margin-right: 5px;"> :<span style="color:navy">'''Summary'''</span> :xxxxx </div> :<span style="color:navy">'''Background'''</span> :xxxxxx :<span style="color:navy">'''Diagnostic Use'''</span> *xxxxx -----") |
No edit summary |
||
Line 5: | Line 5: | ||
:<span style="color:navy">'''Summary'''</span> | :<span style="color:navy">'''Summary'''</span> | ||
: | :CD7 is a pan T-cell marker that is useful for identifying T cells at very early stages of maturation. However, its value is limited by a high frequency of aberrant expression by other lineages that means caution is required in its interpretation | ||
:In some mature T cell disorders variation of expression of CD7 can have diagnostic value | |||
Line 13: | Line 14: | ||
:<span style="color:navy">'''Background'''</span> | :<span style="color:navy">'''Background'''</span> | ||
: | :CD7 is a transmembrane protein that supports T cell interactions with B cells during lymphoid development. Expression is acquired during thymic development of T cells appearing before other t-lineage markers, and expression is retained by mature t cells. | ||
Revision as of 15:10, 13 May 2023
- Summary
- CD7 is a pan T-cell marker that is useful for identifying T cells at very early stages of maturation. However, its value is limited by a high frequency of aberrant expression by other lineages that means caution is required in its interpretation
- In some mature T cell disorders variation of expression of CD7 can have diagnostic value
- Background
- CD7 is a transmembrane protein that supports T cell interactions with B cells during lymphoid development. Expression is acquired during thymic development of T cells appearing before other t-lineage markers, and expression is retained by mature t cells.
- Diagnostic Use
- xxxxx