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CD5: Difference between revisions

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(Created page with " <div style="background-color: #E0EEEE; {{round corners}} padding: 2em 2em; margin-right: 5px;"> :<span style="color:navy">'''Summary'''</span> :'''For mature B cell neoplasms''': CD5 is used to indicate likely CLL or MCL. However, expression is present on a subset of normal B cells, and also less frequently on other lymphoma types. Full interpretation therefore requires consideration of clonality and other markers. :'''In acute lymphoblastic leukaemia''': CD5 is u...")
 
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:<span style="color:navy">'''Summary'''</span>
:<span style="color:navy">'''Summary'''</span>


:'''For mature B cell neoplasms''': CD5 is used to indicate likely CLL or MCL. However, expression is present on a subset of normal B cells, and also less frequently on other lymphoma types. Full interpretation therefore requires consideration of clonality and other markers.  
:For mature B cell neoplasms: CD5 is used to indicate likely CLL or MCL. However, expression is present on a subset of normal B cells, and also less frequently on other lymphoma types. Full interpretation therefore requires consideration of clonality and other markers.  


:'''In acute lymphoblastic leukaemia''': CD5 is useful to indicate T lineage, with (relatively) low levels of aberrant expression.
:In acute lymphoblastic leukaemia: CD5 is useful to indicate T lineage, with (relatively) low levels of aberrant expression.


   
   

Revision as of 17:10, 30 April 2023


Summary
For mature B cell neoplasms: CD5 is used to indicate likely CLL or MCL. However, expression is present on a subset of normal B cells, and also less frequently on other lymphoma types. Full interpretation therefore requires consideration of clonality and other markers.
In acute lymphoblastic leukaemia: CD5 is useful to indicate T lineage, with (relatively) low levels of aberrant expression.



Normal expression and function

xxxxx


Diagnostic role

  • xxxxx



Other relevant information:

xxxxx



SUMMARY TABLES