CD45: Difference between revisions
From haematologyetc.co.uk
No edit summary |
No edit summary |
||
Line 67: | Line 67: | ||
{| class=wikitable style="text-align: left; font-size:80%; width: 25%; height: 30px; | {| class=wikitable style="text-align: left; font-size:80%; width: 25%; height: 30px; | ||
|style= "width: 16.6%; background: #FFE4E1; | | |style= "width: 16.6%; background: #FFE4E1; |Few reported studies (though likely rare) | ||
|} | |} | ||
{| class=wikitable style="text-align: left; font-size:80%; width: 25%; height: 30px; | {| class=wikitable style="text-align: left; font-size:80%; width: 25%; height: 30px; |
Revision as of 10:36, 30 April 2023
SUMMARY TABLES
CD13 expression: primitive cell types | ||||||
---|---|---|---|---|---|---|
AML | B ALL | Burkitt | T ALL | ETP ALL (i) | MPAL i | Hgns i |
Limited Rare Possible Likely Frequent Expected | ? <5% 5-20% 20-40% 40-80% 80-100% | Possible | Rare | Likely | Likely | Possible |
Notes: The main application is in AML (see notes for expression). Aberrant expression is seen in ALL - particularly in B-lineage, although it may be less likely in Burkitt lymphoma. CD13 is not generally expressed in T-ALL, but in the correct context CD13 expression can indicate MPAL or ETP-ALL. CD13 is reported to be expressed by some haematognes (click (i) for additional information)
CD13 expression: mature B cell neoplasms* | ||||||
---|---|---|---|---|---|---|
CLL | MCL | FL | MZL | HCL | LPL | PCL |
rare | rare | rare | rare | rare | rare | rare |
Notes: overall expression is uncommon in mature B-lymphoproliferative disorders, but may occur at plasma cell differentiation
CD13 expression: mature T cell neoplasms* | ||||||
---|---|---|---|---|---|---|
ATLL | CTCL/Sezary | T-PLL | T-LGL | NK-LGL | ||
limited | limited | limited | limited | limited |
Notes: There is limited published evidence, but reports suggest expression of CD13 is uncommon in mature T cell malignancy
KEY
1. Colour key: - the likelihood of any individual case expressing this marker, indicated by colour:
Few reported studies (though likely rare) |
Expression may be seen, but is rare (<5%) |
Expression occurs in some cases (5-20%) |
Expression is likely to be encountered (20-40%) |
Epression is frequent (40-80%) |
Expect expression in most cases (80-100%) |