CD43

Summary

Diagnostically the vlaue of CD43 relates to its variable expression between different B-lymphocyte neoplasms that gives it some diagnostic value in the recognition of CLL.

Background

CD43 sialophorin that is widely expressed accross T lymphocytes, monocytes and granulocytes. In the B-cell lineage however CD43 has vaiable expression being mainly present on normal activated b lymphocytes, but absent from resting B cells.

Diagnostic Use

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