CD41
From haematologyetc.co.uk
- Summary
- A reliable and specific marker that can be used to identify megakaryocyte lineage characteristics.
- Background
CD41 and CD61 respectively represent the alpha or beta chains that together form the IIbIIIa receptor that mediates the binding of activated platelets to fibrinogen during platelet aggregation.
- Diagnostic Use
- The alpha IIb only forms part of this receptor and therefore has very good specificity for identifying megakaryocytic differentiation