CD14: Difference between revisions
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:<span style="color:navy">'''Summary'''</span> | :<span style="color:navy">'''Summary'''</span> | ||
:CD14 aids recognition of bacteria by cells of monocytic lineage, it is regarded as a pan-monocyte antigen. Expression of CD14 is not restricted to malignant cells | :CD14 aids recognition of bacteria by cells of monocytic lineage, it is regarded as a pan-monocyte antigen. Expression of CD14 is not restricted to malignant cells as it is also expressed by normal and reactive monocytes | ||
:when expressed in aml CD14 is a marker of monocytic lineage, but absence of CD14 expression does not preclude monocytic lineage in AML and CMML since some typical monoblasts may not express this marker | :when expressed in aml CD14 is a marker of monocytic lineage, but absence of CD14 expression does not preclude monocytic lineage in AML and CMML since some typical monoblasts may not express this marker | ||
Revision as of 12:50, 6 May 2023
- Summary
- CD14 aids recognition of bacteria by cells of monocytic lineage, it is regarded as a pan-monocyte antigen. Expression of CD14 is not restricted to malignant cells as it is also expressed by normal and reactive monocytes
- when expressed in aml CD14 is a marker of monocytic lineage, but absence of CD14 expression does not preclude monocytic lineage in AML and CMML since some typical monoblasts may not express this marker
Normal expression and function
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Diagnostic role
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Other relevant information:
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SUMMARY TABLES