| Marker patterns in typical acute myeloid leukaemia
|
| CD45 expression in AML
|
| Typically expression of CD45 is less intense than normal T or B cells, with many cases showing variable expression with a wide spread of CD45 intensity.
|
| Markers of pimitive cell type expected in AML
|
| Marker
|
Expectation
|
Comment
|
| CD34
|
|
Frequently expressed, most often in less differentiated forms of AML. Expression often less intense than in lymphoid leukaemias
|
| TdT
|
|
Expressed particularly in less differentiated forms of AML. Often on a sub-population of cells; expression usually less intense than in lymphoid leukaemias
|
| CD7
|
|
Characteristic of CLL, usually less strong than on T cells
|