Acute leukaemia types
From haematologyetc.co.uk
| Marker patterns in typical acute myeloid leukaemia | |||
|---|---|---|---|
| CD45 expression in AML | |||
| Typically expression of CD45 is less intense than normal T or B cells, with many cases showing variable expression with a wide spread of CD45 intensity. | |||
| Markers of pimitive cell type expected in AML | |||
| Marker | Expectation | Comment | |
| CD34 | Expression is expected, but less strong than normal B cells | ||
| TdT | Expect weak restricted κ or λ or absent expression | ||
| CD7 | Characteristic of CLL, usually less strong than on T cells | ||