Acute leukaemia types: Difference between revisions
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|colspan="1" style = "font-size:90%; color:black;" |'''CD34''' | |colspan="1" style = "font-size:90%; color:black;" |'''CD34''' | ||
|colspan="1" style = "background:#004466;"| | |colspan="1" style = "background:#004466;"| | ||
|colspan="1" style = "font-size:84%;"| | |colspan="1" style = "font-size:84%;"|frequently expressed most often in less differentiated forms of AML; expression often less intense than in lymphoid leukaemias | ||
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|colspan="1" style = "width: 4%; font-size:90%; color:black;" |'''TdT''' | |colspan="1" style = "width: 4%; font-size:90%; color:black;" |'''TdT''' | ||
Revision as of 12:11, 17 July 2023
| Marker patterns in typical acute myeloid leukaemia | |||
|---|---|---|---|
| CD45 expression in AML | |||
| Typically expression of CD45 is less intense than normal T or B cells, with many cases showing variable expression with a wide spread of CD45 intensity. | |||
| Markers of pimitive cell type expected in AML | |||
| Marker | Expectation | Comment | |
| CD34 | frequently expressed most often in less differentiated forms of AML; expression often less intense than in lymphoid leukaemias | ||
| TdT | Expect weak restricted κ or λ or absent expression | ||
| CD7 | Characteristic of CLL, usually less strong than on T cells | ||