Actions

Acute leukaemia types: Difference between revisions

From haematologyetc.co.uk

No edit summary
No edit summary
Line 13: Line 13:
|colspan="1" style = "font-size:80%; width: 80%; |'''Comment'''
|colspan="1" style = "font-size:80%; width: 80%; |'''Comment'''
|-
|-
|colspan="1" style = "font-size:90%; color:black;" |'''CD19'''
|colspan="1" style = "font-size:90%; color:black;" |'''CD34'''
|colspan="1" style = "background:#004466;"|
|colspan="1" style = "background:#004466;"|
|colspan="1" style = "font-size:84%;"|Expression is expected, but less strong than normal B cells
|colspan="1" style = "font-size:84%;"|Expression is expected, but less strong than normal B cells
|-
|-
|colspan="1" style = "width: 4%; font-size:90%; color:black;" |'''κ/λ'''
|colspan="1" style = "width: 4%; font-size:90%; color:black;" |'''TdT'''
|colspan="1" style = "width: 8%; background:#00b8e6;"|
|colspan="1" style = "width: 8%; background:#00b8e6;"|
|colspan="1" style = "font-size:80%;"|Expect weak restricted κ or λ or absent expression
|colspan="1" style = "font-size:80%;"|Expect weak restricted κ or λ or absent expression
|-
|-
|colspan="1" style = "font-size:90%; color:black;" |'''CD5'''
|colspan="1" style = "font-size:90%; color:black;" |'''CD7'''
|colspan="1" style = "background:#004466;"|
|colspan="1" style = "background:#004466;"|
|colspan="1" style = "font-size:80%;"|Characteristic of CLL, usually less strong than on T cells
|colspan="1" style = "font-size:80%;"|Characteristic of CLL, usually less strong than on T cells

Revision as of 12:04, 17 July 2023

Marker patterns in typical acute myeloid leukaemia
CD45 expression in AML
Typically expression of CD45 is less intense than normal T or B cells, with many cases showing variable expression with a wide spread of CD45 intensity.
Markers of pimitive cell type expected in AML
Marker Expectation Comment
CD34 Expression is expected, but less strong than normal B cells
TdT Expect weak restricted κ or λ or absent expression
CD7 Characteristic of CLL, usually less strong than on T cells