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Acute leukaemia types: Difference between revisions

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!colspan="4" style = "font-size:110%; color: navy; text-align:center; background:#DEE0DE;"|'''Marker patterns in typical acute myeloid leukaemia'''
!colspan="4" style = "font-size:110%; color: navy; text-align:center; background:#DEE0DE;"|'''Marker patterns in typical acute myeloid leukaemia'''
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!colspan="4" style = "font-size:90%; background:#DAE8F2"|'''CD45''' expression
!colspan="4" style = "font-size:90%; background:#DAE8F2"|'''CD45 expression in AML'''
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|colspan="4" style = "font-size:90%; color:black;" |Typically expression of CD45 is less intense than normal T or B cells, with many cases showing variable expression with a wide spread of CD45 intensity.
|colspan="4" style = "font-size:90%; color:black;" |Typically expression of CD45 is less intense than normal T or B cells, with many cases showing variable expression with a wide spread of CD45 intensity.

Revision as of 12:03, 17 July 2023

Marker patterns in typical acute myeloid leukaemia
CD45 expression in AML
Typically expression of CD45 is less intense than normal T or B cells, with many cases showing variable expression with a wide spread of CD45 intensity.
Markers of pimitive cell type expected in AML
Marker Expectation Comment
CD19 Expression is expected, but less strong than normal B cells
κ/λ Expect weak restricted κ or λ or absent expression
CD5 Characteristic of CLL, usually less strong than on T cells