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TCRγδ: Difference between revisions

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(Created page with " <div style="background-color: #E0EEEE; {{round corners}} padding: 2em 2em; margin-right: 5px;"> :<span style="color:navy">'''Summary'''</span> :The αβ TCR is the primary form in health accounting for around 95% of circulating T cells. Alteration of that normal expression pattern may suggest a neoplastic or inflammatory disorder </div> :<span style="color:navy">'''Background'''</span> :The αβ chains expressed are expressed as part of the T-cell receptor (TCR...")
 
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<div style="background-color: #E0EEEE; {{round corners}} padding: 2em 2em;  margin-right: 5px;">
:<span style="color:navy">'''Summary'''</span>
:The αβ TCR is the primary form in health accounting for around 95% of circulating T cells. Alteration of that normal expression pattern may suggest a neoplastic or inflammatory disorder
</div>
:<span style="color:navy">'''Background'''</span>
:The αβ chains expressed are expressed as part of the T-cell receptor (TCR) complex - these are the antigen recognising parts of the complex. T cells expressing this receptor are referred to as αβ T cells.
:<span style="color:navy">'''Diagnostic Use'''</span>
*Significant populations expressing gd chains may indicate autoimmune or inflammaotory disease
*γδ restriction or predominance may suggest a γδ lymphoma
*Absence of αβ or γδ is found in NK lineage disorders
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Revision as of 21:26, 14 May 2023

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