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{| class="wikitable" style="border-style: solid; border-width: 5px; border-color: #023020; color:black"
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|colspan="1" style = "font-size:100%; color:black; background: #afbddb |'''Overview of malaria lifecycle'''
'''Navigation'''</br>
<span style="font-size:90%">[[Malaria Index|Return to Malaria main index]]''</span></br>
 
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{| class="wikitable" style="border-style: none; border-width: 2px; border-color: gainsboro; color:black"
|colspan="1" style = "font-size:100%; color:black; background: gainsboro |'''Overview'''
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<gallery mode="nolines" widths=300px heights=400px>
File:New_Malaria_Lifecycle.jpg|<span style="font-size:90%"></span>|link={{filepath:New_Malaria_Lifecycle.jpg}}
</gallery>
</br>
{| class="wikitable" style="border-style: none; border-width: 2px; border-color: gainsboro; color:black"
|colspan="1" style = "font-size:100%; color:black; background: gainsboro |'''Descriptions'''
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The lifecycle of malaria is shown below. Parasites move from the mosquito to mammal host, then back again (click on the image for a size version).
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1. '''Initial infection of the human host'''</br><span style="font-size:90%">The initial stage following the mosquito bite during which infection is established and from which re-crudescence of infection may recrudesce</span></br>
Knowledge of each stage is useful since each has clinical, and often morphological relevance (see links later in the section)
<span style="font-size:200%">&#x2192;</span> [[Pre-erythrocytic (liver) stage|Click for more about this stage]]
 
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2. '''The trophozoite stage'''</br><span style="font-size:90%">This is the initial growth stage where the ring form grows, often chhanges, and modifies the erythocyte, the characteristic morphological features of species develop during this stage.</br>
<span style="font-size:200%">&#x2192;</span> [[Biology of the trophozoite stage|Click for more about this stage]]
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3. '''The schizont stage'''</br><span style="font-size:90%">This is the asexual replication stage that has significant variabilty as they mature, it is the stage responsible for intermittent fevers in some malaria cases.</br>
<span style="font-size:200%">&#x2192;</span> [[Biology of the schizont|Click for more about this stage]]
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4. '''The Gametocyte stage'''</br><span style="font-size:90%">This is the sexual replication stage with male and female parasite forms that will replicate within the mosquito, this stage may also persist following treatment.</br>
<gallery mode="nolines" widths=300px heights=400px>
<span style="font-size:200%">&#x2192;</span> [[Biology of the gametocyte|Click for more about this stage]]
File:Malaria-Lifecycle.jpg|<span style="font-size:90%">''Infection of the mosquito''</span>|link={{filepath:Malaria-Lifecycle.jpg}}
</gallery>
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5. '''Re-infection of mosquito'''</br><span style="font-size:90%">Sexual replication of malarial parasites occurs when gametocytes encounter conditions in the mosquito stomach - it may also be seen stored samples (exflagellation).</br>
{| class="wikitable" style="border-style: solid; border-width: 5px; border-color: #023020; color:black"
<span style="font-size:200%">&#x2192;</span> [[Re-infection of the mosquito|Click for more about this stage]]
|colspan="1" style = "font-size:100%; color:black; background: #afbddb |'''More detailed information'''
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*[[Pre-erythrocytic (liver) stage]]: understand the incubation period and re-crudecence of infection in some species
*Biology of the trohozoite stage
*[[Biology of the schizont]]
*Biology of the gametocyte
*[[Re-infection of the mosquito]]
*The host response to malaria
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Latest revision as of 18:35, 2 November 2024


Navigation
Return to Malaria main index


Overview


Descriptions


1. Initial infection of the human host
The initial stage following the mosquito bite during which infection is established and from which re-crudescence of infection may recrudesce
Click for more about this stage


2. The trophozoite stage
This is the initial growth stage where the ring form grows, often chhanges, and modifies the erythocyte, the characteristic morphological features of species develop during this stage.
Click for more about this stage


3. The schizont stage
This is the asexual replication stage that has significant variabilty as they mature, it is the stage responsible for intermittent fevers in some malaria cases.
Click for more about this stage


4. The Gametocyte stage
This is the sexual replication stage with male and female parasite forms that will replicate within the mosquito, this stage may also persist following treatment.
Click for more about this stage


5. Re-infection of mosquito
Sexual replication of malarial parasites occurs when gametocytes encounter conditions in the mosquito stomach - it may also be seen stored samples (exflagellation).
Click for more about this stage