CD41: Difference between revisions
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:<span style="color:navy">'''Summary'''</span> | :<span style="color:navy">'''Summary'''</span> | ||
: | :A reliable and specific marker that can be used to identify megakaryocyte lineage characteristics. | ||
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:<span style="color:navy">'''Background'''</span> | :<span style="color:navy">'''Background'''</span> | ||
*CD41 and CD61 respectively represent the alpha or beta chains that together form the IIbIIIa receptor that mediates the binding of activated platelets to fibrinogen during platelet aggregation. | |||
:<span style="color:navy">'''Diagnostic Use'''</span> | :<span style="color:navy">'''Diagnostic Use'''</span> | ||
* | *The alpha IIb only forms part of this receptor and therefore has very good specificity for identifying megakaryocytic differentiation | ||
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Revision as of 09:05, 11 May 2023
- Summary
- A reliable and specific marker that can be used to identify megakaryocyte lineage characteristics.
- Background
- CD41 and CD61 respectively represent the alpha or beta chains that together form the IIbIIIa receptor that mediates the binding of activated platelets to fibrinogen during platelet aggregation.
- Diagnostic Use
- The alpha IIb only forms part of this receptor and therefore has very good specificity for identifying megakaryocytic differentiation