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Combined display of all available logs of haematologyetc.co.uk. You can narrow down the view by selecting a log type, the username (case-sensitive), or the affected page (also case-sensitive).
- 13:20, 5 January 2024 John talk contribs created page Tables of diagnostic patterns associated with aberrancy or alternative diagnosis in AML (Created page with "---- <div style="width: 200px"> {| class="wikitable" style="border-left:solid 5px green;border-right:solid 5px green;border-top:solid 5px black;border-bottom:solid 5px black; font-size:90%; color:navy" | colspan="1"''|Return to previous page'' |} </div> --------")
- 13:13, 5 January 2024 John talk contribs created page Tables of diagnostic markers supporting assignment of primitive phenotype in AML (Created page with "Markers used to demonstrate primitive nature in AML Atypical patterns of primitive marker expression in acute myeloid leukaemia")
- 12:50, 5 January 2024 John talk contribs created page Tables of diagnostic markers supporting lineage assignment in AML (Created page with " Myeloid lineage-defining markers")
- 13:23, 4 January 2024 John talk contribs created page Flow cytometry:ETP-ALL (Created page with "---- <div style="width: 200px"> {| class="wikitable" style="border-left:solid 5px green;border-right:solid 5px green;border-top:solid 5px black;border-bottom:solid 5px black; font-size:90%; color:navy" | colspan="1"''|Return to previous page'' |} </div> -------- <div style="width: 95%"> {| class="wikitable" style="border-style: solid; border-width: 5px; color:black" |colspan="1" style = "font-size:90%; color:black; background:#ddeee1"|'''1. The primi...")
- 12:59, 4 January 2024 John talk contribs created page ETP-ALL (Created page with "ETPs are recent immigrants from the bone marrow (BM) to the thymus, derived from hematopoietic stem cells, which retain a certain level of multilineage pluripotency.7,8 By gene expression profiling, ETP cells share similarities with hematopoietic stem cells and myeloid progenitor cells.5 The definition of ETP-ALL/LBL is based on the immunophenotype of the leukemic cells, which are typically CD1a−, CD8−, CD5− (dim), and positive for 1 or more stem cell or myeloid...")
- 14:02, 2 January 2024 John talk contribs created page Flow cytometry:BPDCN (Created page with "---- <div style="width: 200px"> {| class="wikitable" style="border-left:solid 5px green;border-right:solid 5px green;border-top:solid 5px black;border-bottom:solid 5px black; font-size:90%; color:navy" | colspan="1"''|Return to previous page'' |} </div> ---- <div style="width: 95%"> {| class="wikitable" style="border-style: solid; border-width: 5px; color:black" |colspan="1" style = "font-size:90%; color:black; background:#ddeee...")
- 15:11, 31 December 2023 John talk contribs created page Flow cytometry:ALAL-NOS (Created page with "---- <div style="width: 200px"> {| class="wikitable" style="border-left:solid 5px green;border-right:solid 5px green;border-top:solid 5px black;border-bottom:solid 5px black; font-size:90%; color:navy" | colspan="1"''|Return to previous page'' |} </div> ---- Reserved for cases where a primitive haematopoietic malignancy is established but where confident assignment to any specific category is not possible. This diagnosis is rar...")
- 15:32, 22 December 2023 John talk contribs created page BPDCN (Created page with "Blastic plasmacytoid dendritic cell neoplasm (BPDCN) expresses CD4, CD56 (bright), CD36, CD38, CD43, CD45, CD71, HLA-DR, as well as plasmacytoid dendritic cell (PDC) associated markers (CD123, CD303, CD304, TCF4, TCL1) (2, 18). CD45 expression may range from dim to moderate. SSC of the tumor cells is usually low. CD7 and CD33 are relatively commonly expressed. TdT is positive in approximately one-third of the cases, and occasional cases may express CD117. Based on the WH...")
- 15:27, 22 December 2023 John talk contribs created page Flow cytometry:Acute Leukaemia of ambiguous lineage not otherwise sepcified (Created page with "---- <div style="width: 200px"> {| class="wikitable" style="border-left:solid 5px green;border-right:solid 5px green;border-top:solid 5px black;border-bottom:solid 5px black; font-size:90%; color:navy" | colspan="1"''|Return to previous page'' |} </div> ----")
- 14:33, 22 December 2023 John talk contribs created page Flow Cytometry:T-Lymphoid lineage assignment (Created page with "---- <div style="width: 200px"> {| class="wikitable" style="border-left:solid 5px green;border-right:solid 5px green;border-top:solid 5px black;border-bottom:solid 5px black; font-size:90%; color:navy" | colspan="1"''|Return to previous page'' |} </div> ----")
- 14:28, 22 December 2023 John talk contribs created page Flow Cytometry:B-lymphoid lineage assignment (Created page with "---- <div style="width: 200px"> {| class="wikitable" style="border-left:solid 5px green;border-right:solid 5px green;border-top:solid 5px black;border-bottom:solid 5px black; font-size:90%; color:navy" | colspan="1"''|Return to previous page'' |} </div> ----")
- 14:26, 22 December 2023 John talk contribs created page Flow Ctrometry:B-lymphoid lineage assignment (Created page with "---- <div style="width: 200px"> {| class="wikitable" style="border-left:solid 5px green;border-right:solid 5px green;border-top:solid 5px black;border-bottom:solid 5px black; font-size:90%; color:navy" | colspan="1"''|Return to previous page'' |} </div> ----")
- 14:14, 22 December 2023 John talk contribs created page Flow Cytometry:Myeloid lineage assignment (Created page with "---- <div id="MPAL_Table1">'''Table 1'''</div> '''MYELOID LINEAGE ASSIGNMENT''' <span id="anchor_0"></span>. <div style="width: 100%; border: 1px solid black; font-size:100%"> {| class="wikitable" style="color:black; background-color:#ffffff;" cellpadding="0" !colspan="2" <span style="font-size:90%; font-color:navy; style="text-align: left; border: 1px solid black; background:pale gray">|'''Requirements to assign myeloid lineage in MPAL'''</br></span> <div class="mw-c...")
- 11:29, 22 December 2023 John talk contribs created page Flow cytometry:AUL (Created page with "---- <div style="width: 200px"> {| class="wikitable" style="border-left:solid 5px green;border-right:solid 5px green;border-top:solid 5px black;border-bottom:solid 5px black; font-size:90%; color:navy" | colspan="1"''|Return to previous page'' |} </div> ---- <span id="anchor_0"></span>. <div style="width: 100%; border: 1px solid black; font-size:100%"> {| class="wikitable" style="color:black; background-color:#ffffff;" cellpad...")
- 11:19, 22 December 2023 John talk contribs created page Flow cytometry:MPAL (Created page with "---- '''Important Note''' MPAL is uncommon (2-3% of acute leukaemia). Flow cytometry provides initial evidence of MPAL. However conclusions may subsequently be modified (e.g. by results of immunohistochemistry, cytogenetics, or genetics). It is important that the provisional nature of flow cytometry assignment of MPAL is acknowledged. Note that MPAL includes two components that can be considered separately: (1) '''Mixed Phenotype''' - ineage assignment is possible b...")
- 14:46, 21 December 2023 John talk contribs created page Myeloid lineage-associated markers (Created page with "---- <div style="width: 200px"> {| class="wikitable" style="border-left:solid 5px green;border-right:solid 5px green;border-top:solid 5px black;border-bottom:solid 5px black; font-size:90%; color:navy" | colspan="1"''|Return to previous page'' |} </div> ---- '''Table: Marker patterns that allow definite assignment of acute myeloid lineage''' <div style="width: 95%"> {| class="wikitable" style="border-style: solid; border-width:...")
- 14:42, 21 December 2023 John talk contribs created page Myeloid lineage-defining markers (Created page with "---- <div style="width: 200px"> {| class="wikitable" style="border-left:solid 5px green;border-right:solid 5px green;border-top:solid 5px black;border-bottom:solid 5px black; font-size:90%; color:navy" | colspan="1"''|Return to previous page'' |} </div> ---- '''Table: Marker patterns that allow definite diagnosis of acute myeloid leukaemia''' <div style="width: 95%"> {| class="wikitable" style="border-style: solid; border-width...")
- 17:45, 20 December 2023 John talk contribs created page Additional immunophenotypic markers useful in lineage assignment or subtyping of AML (Created page with "<div id="AML_Table2B">'''Table 2B'''</div> <div style="width: 95%"> {| class="mw-collapsible mw-collapsed wikitable" style="border-style: solid; border-width: 5px; color:black" data-expandtext="Click to open Table" data-collapsetext="Click to close table" !colspan="2" <span style="font-size:100%; colour:white; text-align:left; border: 1px solid black; background:pale gray">|Myeloid lineage-associated markers (Specific differentiation)'''</span><span style="font-size:90%;...")
- 15:04, 20 December 2023 John talk contribs created page Immnophenotypic markers in AML (Created page with "---- <div style="width: 200px"> {| class="wikitable" style="border-left:solid 5px green;border-right:solid 5px green;border-top:solid 5px black;border-bottom:solid 5px black; font-size:90%; color:navy" | colspan="1"''|Return to previous page'' |} </div> ---- <div style="width: 95%"> {| class="wikitable" style="border-style: solid; border-width: 5px; color:black" ! colspan="2" style = "font-size:100%; color:black"| '''Table:''' M...")
- 12:24, 15 December 2023 John talk contribs uploaded File:AMLM5B.jpg
- 12:24, 15 December 2023 John talk contribs created page File:AMLM5B.jpg
- 12:24, 15 December 2023 John talk contribs created page File:AMLM5A.jpg
- 12:24, 15 December 2023 John talk contribs uploaded File:AMLM5A.jpg
- 18:58, 11 December 2023 John talk contribs created page Atypical patterns of primitive marker expression in acute myeloid leukaemia (Created page with "<div style="width: 180px"> {| class="wikitable" style="border-left:solid 5px green;border-right:solid 5px green;border-top:solid 5px black;border-bottom:solid 5px black;" | colspan="1"''|Click to return to AML diagnosis page'' |} </div> <div style="width: 95%"> {| class="wikitable" style="border-style: solid; border-width: 5px; color:black" ! colspan="2" style = "font-size:100%; color:black"| '''Table:''' Markers primarily used t...")
- 18:57, 11 December 2023 John talk contribs created page Atypical patterns of primitive marker expression in acute leukaemia (Created page with "<div style="width: 180px"> {| class="wikitable" style="border-left:solid 5px green;border-right:solid 5px green;border-top:solid 5px black;border-bottom:solid 5px black;" | colspan="1"''|Click to return to AML diagnosis page'' |} </div> <div style="width: 95%"> {| class="wikitable" style="border-style: solid; border-width: 5px; color:black" ! colspan="2" style = "font-size:100%; color:black"| '''Table:''' Markers primarily used t...")
- 18:56, 11 December 2023 John talk contribs created page Markers used to demonstrate primitive nature in AML (Created page with "<div style="width: 180px"> {| class="wikitable" style="border-left:solid 5px green;border-right:solid 5px green;border-top:solid 5px black;border-bottom:solid 5px black;" | colspan="1"''|Click to return to AML diagnosis'' |} </div> <div style="width: 95%"> {| class="wikitable" style="border-style: solid; border-width: 5px; color:black" ! colspan="2" style = "font-size:100%; color:black"| '''Table:''' Markers primarily used to con...")
- 17:23, 1 December 2023 John talk contribs created page Table (Created page with "<div style="width: 95%"> {| class="mw-collapsible mw-collapsed wikitable" style="border-style: solid; border-width: 5px; color:black" </br>data-expandtext="Click to open Table" data-collapsetext="Click to close table" ! colspan="2" style = "font-size:100%; color:black"| '''Table:''' Markers primarily used to confirm primitive nature in AML. |- |colspan="2" style = "font-size:90%; color:black; background:#ddeee1"|The expression of some markers is typically associa...")
- 16:59, 28 November 2023 John talk contribs created page The flow cytometric diagnosis of AML (Created page with "Do the cells have flow cytometric features of primitive cells? *Typically these will be (for more detail see table) *In some cases there may be atypical features (for more detail see table) ---- Can we confirm myeloid nature? *Typical cases can generally be recognised by (see table for details) *Atypical cases can still be identified based on a minimal feature set (see table for details) *In unusual cases an extended marker panel may allow lineage assignment (see Table f...")
- 16:54, 30 October 2023 John talk contribs created page AUL (Created page with "<span id="anchor_0"></span>. <div style="width: 100%; border: 1px solid black; font-size:100%"> {| class="wikitable" style="color:black; background-color:#ffffff;" cellpadding="0" !colspan="2" <span style="font-size:90%; font-color:navy; style="text-align: left; border: 1px solid black; background:pale gray">|'''What features must be met to diagnose acute undifferentiated leukaemia'''</br></span> <div class="mw-collapsible mw-collapsed" data-expandtext="Click for expl...")
- 11:06, 18 October 2023 John talk contribs uploaded File:AML M2.png
- 11:06, 18 October 2023 John talk contribs created page File:AML M2.png
- 11:03, 18 October 2023 John talk contribs created page File:AML M1.png
- 11:03, 18 October 2023 John talk contribs uploaded File:AML M1.png
- 12:49, 17 October 2023 John talk contribs created page CD71 (Created page with " <div style="background-color: #E0EEEE; {{round corners}} padding: 2em 2em; margin-right: 5px;"> :<span style="color:navy">'''Summary'''</span> :CD71 has value in the recognition of erythroid differentiation in AML where expression levels can be strong. However, it is not fully specific and may also be a maker of high levels of proliferation. Expression is frequent on other AML subtypes including APL and other lineages including cases of ALL. For this reason the mark...")
- 12:29, 17 October 2023 John talk contribs created page CD36 (Created page with " <div style="background-color: #E0EEEE; {{round corners}} padding: 2em 2em; margin-right: 5px;"> :<span style="color:navy">'''Summary'''</span> :The main practical use for is in the recognition of megakaryocytic lineage, where expression is expected. However this cell surface receptor has a range of ligands and is expressed on other cells including those of monocyte macrophage lineage so the lineage specificity is not solely for this lineage. </div> :<span style...")
- 18:14, 5 October 2023 John talk contribs created page Important elements in acute myeloid leukaemia diagnosis (Created page with "1. Flow cytometric typing of acute leukaemia should always be regarded as provisional.''' The initial findings of flow cytometry can direct initial treatment. However, blast cell count and lineage may sometimes be subject to modification as other evidence emerges. Reporting should reflect this.</span> ---- 2. It is important to establish that the cells analused have characteristics of primitive "blast cells" Several methods may be used (ideally together) these inclu...")
- 11:30, 2 October 2023 John talk contribs created page Image Index of red cell forms (Created page with "{|style="float:left; width: 250px; height: 25px; text-align:center; font-style: normal; color: gray; background: #EEEFF7; border-style: solid; border-width: 1px; margin: 1px" | Go to Image index <span style="color:navy">Go to alphabetical list</span> |} <br /> <br /> ---- '''1. Terms applied to groups of red cells''' <gallery mode="nolines" widths="140px" heights="140px" > File:RC_C_agglutination_...")
- 09:21, 28 July 2023 John talk contribs created page ALT (Created page with "---- '''Sections''' *<span style="font-size:90%;>Markers of "primitive nature": go to section</span> *<span style="font-size:90%;>Core markers of most cases: go to section</span> *<span style="font-size:90%;>Aberrant markers often seen: go to section</span> *<span style="font-size:90%;>Notes 1: specific subtypes: go to section</span> *<span style="font-size:90%;>Notes 2: ambiguous lineage [[#anchor_5|go to section]...")
- 18:53, 26 July 2023 John talk contribs created page MPAL (Created page with "<span id="anchor_0"></span>. <div style="width: 100%; border: 1px solid black; font-size:100%"> {| class="wikitable" style="color:black; background-color:#ffffff;" cellpadding="0" !colspan="2" <span style="font-size:90%; font-color:navy; text-align:center; border: 1px solid black; background:pale gray">|'''MARKERS USEFUL TO CONFIRM PRIMITIVE NATURE OF BLAST CELLS'''</br></span> |- |colspan="2" style = "font-size:90%; color:black; background:#ddeee1" |'''Useful mark...")
- 11:58, 17 July 2023 John talk contribs created page Acute leukaemia types (Created page with "<div style="width: 95%; overflow: auto; border: 1px solid navy; font-size:100%"> {| class="wikitable" style="color:black; background-color:#ffffff;" cellpadding="5" !colspan="4" style = "font-size:110%; color: navy; text-align:center; background:#DEE0DE;"|'''Marker patterns in typical acute myeloid leukaemia''' |- !colspan="4" style = "font-size:90%; background:#DAE8F2"|'''CD45''' expression |- |colspan="4" style = "font-size:90%; color:black;" |Typically expression of C...")
- 18:10, 14 July 2023 John talk contribs created page Flow cytometry: Plasma cells (Created page with "---- <gallery mode="nolines" widths="200px" heights="200px" border="1px" > file:PC.jpg|link={{filepath:PC.jpg}} </gallery> ---- <span style="color: navy>'''Background to flow cytometric diagnosis'''</span> Differentiation to plasma cells involves (in mast cases) the loss of typical pan B-cell markers and surface light chains. The expression of CD45 also differs both within and between cases making standard gating strategies difficult to apply. Cells are most often id...")
- 16:04, 14 July 2023 John talk contribs created page Flow cytometry: Lymphoplasmacytic Lymphoma (Created page with "---- 200px|link=LPL.jpg <span style="color: navy>'''Background to flow cytometric diagnosis'''</span> Cells of LPL share features of mature B-cell differentation and features of early plasma cell differentiation, and have mixed populations with features of each (although proportions vary). This can be a challenging diagnosis by flow cytometry alone, but other modalities can generally make this diagnosis clear. <div style="width: 95%; overflow: a...")
- 10:55, 14 July 2023 John talk contribs created page Flow cytomtery: Lymphoplasmacytic lymphoma (Created page with "---- 200px|link=LPL.jpg <span style="color: navy>'''Background to flow cytometric diagnosis'''</span> Cells of LPL share features of mature B-cell differentation and features of early plasma cell differentiation, and have mixed populations with features of each (although proportions vary). This can be a challenging diagnosis by flow cytometry alone, but other modalities can generally make this diagnosis clear. <div style="width: 95%; overflow: a...")
- 17:29, 13 July 2023 John talk contribs created page Marker expression in B-lymphoproliferative disorders (Created page with "test ---- '''Marker patterns of B-Cell Lymphoproliferative disorders''' *Chronic lymphocytic leukaemia *Mantle Cell Lymphoma *Follicular Lymphoma *Marginal Zone Lymphoma *Hairy Cell Leukaemia *Flow cytometry: Diffuse Large B-cell Lymphoma|Diffus...")
- 16:58, 13 July 2023 John talk contribs uploaded a new version of File:CD45-PopA.jpg
- 16:55, 13 July 2023 John talk contribs uploaded File:CD45-PopA.jpg
- 16:55, 13 July 2023 John talk contribs created page File:CD45-PopA.jpg
- 14:49, 13 July 2023 John talk contribs uploaded File:DLBCL.jpg
- 14:49, 13 July 2023 John talk contribs created page File:DLBCL.jpg
- 10:27, 13 July 2023 John talk contribs uploaded File:CD45 populations.jpg