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Pre-erythrocytic (liver) stage

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The schizont pathway


The initial mosquito bite (Image A): blood from the host is taken through as mosquito mouthparts (m) from small vessels (v). At the same time fluid from mosquito salivary glands passes into the vessel. If a mosquitos is host to the malaria organism then parasites enter the blood (in the form of "sporozoites" (sp)).


Initial mosquito infection


The sporozoites that have entered the blood then pass through the blood vessel and into the cells of the liver (B). They may pass through multiple cells but then remain in a single liver cell (C).


Morphological features and relevance




Relevance of schizonts to clinical biology