Red cell size - Revision history

Admin at 20:13, 24 March 2024

2024-03-24T20:13:44Z

← Older revision		Revision as of 22:13, 24 March 2024
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	</gallery>		</gallery>

	Early and trophozoites of ''P.vivax''. The increased size and red cell distortion increase as the parasites mature. In this case the early trophozoite (A) is enlarged but still retains a relatively undistorted shape; however the late form (B) is has a very irregular shape (note there is no fimbriation).		Early and trophozoites of ''P.vivax''. The increased size and red cell distortion increase as the parasites mature. In this case the early trophozoite (A) is enlarged but still retains a relatively undistorted elongated shape (similar to ''P.ovale''); however the late form (B) is has a very irregular shape (note there is no fimbriation).


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Admin at 20:12, 24 March 2024

2024-03-24T20:12:50Z

← Older revision		Revision as of 22:12, 24 March 2024
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	<gallery mode="nolines" widths="200px" heights="220px" >		<gallery mode="nolines" widths="200px" heights="220px" >
	File:~~5SizePVET~~.jpg\|A\|link={{filepath:\|~~5SizePVET~~.jpg}}		File:7SizePVET.jpg\|A\|link={{filepath:\|7SizePVET.jpg}}
	File:~~6SizePVLT~~.jpg\|B\|link={{filepath:~~4SizePVLT~~.jpg}}		File:8SizePVLT.jpg\|B\|link={{filepath:8SizePVLT.jpg}}
	</gallery>		</gallery>

	Early and trophozoites o ''P.vivax''. In ~~each~~ case ~~there~~ is a ~~tendency for red cells to have an ovoid~~ shape ~~and~~ there is ~~distortion of the cytoplasm with sharp projectiosn (~~fimbriation)~~. These orregular and spiky projections differ from the rounded crenation that may be seen in ''P.falciparum''~~.		Early and trophozoites of ''P.vivax''. The increased size and red cell distortion increase as the parasites mature. In this case the early trophozoite (A) is enlarged but still retains a relatively undistorted shape; however the late form (B) is has a very irregular shape (note there is no fimbriation).


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Admin at 20:07, 24 March 2024

2024-03-24T20:07:44Z

← Older revision		Revision as of 22:07, 24 March 2024
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	'''SMALL ROUND RED CELLS'''		'''SMALL ROUND RED CELLS'''

	''P.malariae:''		''P.malariae''

	The red cells in this species remain round and are often small in size		The red cells in this species remain round and are often small in size
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	''P.ovale:''		''P.ovale''

	Expect increased red cell size but this may not be marked; the typical shape is an ovoid shape (hence the name) and there may be characteristic finbriation of cytoplams (that may be limited to one pole of the cell).		Expect increased red cell size but this may not be marked; the typical shape is an ovoid shape (hence the name) and there may be characteristic finbriation of cytoplams (that may be limited to one pole of the cell).
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	''P.vivax''		''P.vivax''

			This species tend to have the largest red cell size that becomes evident at quite and early stage; the typical shape is quite irregular fimbriation is not (generally) seen.

	<gallery mode="nolines" widths="200px" heights="220px" >		<gallery mode="nolines" widths="200px" heights="220px" >
	File:~~3SizePMET~~.jpg\|A\|link={{filepath:\|~~3SizePMET~~.jpg}}		File:5SizePVET.jpg\|A\|link={{filepath:\|5SizePVET.jpg}}
	File:~~4SizePFLT~~.jpg\|B\|link={{filepath:~~4SizePFLT~~.jpg}}		File:6SizePVLT.jpg\|B\|link={{filepath:4SizePVLT.jpg}}
	</gallery>		</gallery>

			Early and trophozoites o ''P.vivax''. In each case there is a tendency for red cells to have an ovoid shape and there is distortion of the cytoplasm with sharp projectiosn (fimbriation). These orregular and spiky projections differ from the rounded crenation that may be seen in ''P.falciparum''.


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Admin at 20:04, 24 March 2024

2024-03-24T20:04:21Z

← Older revision		Revision as of 22:04, 24 March 2024
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	Early (A) and late (B) trophozoites o ''P.ovale''. In each case there is a tendency for red cells to have an ovoid shape and there is distortion of the cytoplasm with sharp projectiosn (fimbriation). These differ from the rounded crenation that may be seen in ''P.falciparum''.		Early (A) and late (B) trophozoites o ''P.ovale''. In each case there is a tendency for red cells to have an ovoid shape and there is distortion of the cytoplasm with sharp projectiosn (fimbriation). These orregular and spiky projections differ from the rounded crenation that may be seen in ''P.falciparum''.


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Admin at 20:03, 24 March 2024

2024-03-24T20:03:38Z

← Older revision		Revision as of 22:03, 24 March 2024
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	''T.''		Early (A) and late (B) trophozoites o ''P.ovale''. In each case there is a tendency for red cells to have an ovoid shape and there is distortion of the cytoplasm with sharp projectiosn (fimbriation). These differ from the rounded crenation that may be seen in ''P.falciparum''.

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Admin at 19:59, 24 March 2024

2024-03-24T19:59:07Z

← Older revision		Revision as of 21:59, 24 March 2024
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	For both ''P.ovale'' and ''P.vivax'' the red cells become progressively enlarged and distorted as the parasites develop. It may not be possible to distingish the species based on red cell appearances, but there are differences which should be looked for.		For both ''P.ovale'' and ''P.vivax'' the red cells become progressively enlarged and distorted as the parasites develop. It may not be possible to distingish the species based on red cell appearances, but there are differences which should be looked for.


	''P.ovale:''		''P.ovale:''

			Expect increased red cell size but this may not be marked; the typical shape is an ovoid shape (hence the name) and there may be characteristic finbriation of cytoplams (that may be limited to one pole of the cell).

	<gallery mode="nolines" widths="200px" heights="220px" >		<gallery mode="nolines" widths="200px" heights="220px" >
	File:~~3SizePMET~~.jpg\|A\|link={{filepath:\|~~3SizePMET~~.jpg}}		File:5SizePOET.jpg\|A\|link={{filepath:\|5SizePOET.jpg}}
	File:~~4SizePFLT~~.jpg\|B\|link={{filepath:~~4SizePFLT~~.jpg}}		File:6SizePOLT.jpg\|B\|link={{filepath:4SizePOLT.jpg}}
	</gallery>		</gallery>

	''The rings are larger and more robust than in ''P.falciparun'', and they enlarge further during parasite development although in this species the characteristic ring appearance can often still be distinguished even late in development. Note that red cells become enlarged and distorted (typically elongation and fimbriation) with characteristic James' dots.''		''T.''

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Admin at 19:41, 24 March 2024

2024-03-24T19:41:03Z

← Older revision		Revision as of 21:41, 24 March 2024
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	The early (A) and late trophozoites (B) shown in this image each lie within round erythrocytes with reduced size.		The early (A) and late trophozoites (B) shown in this image each lie within round erythrocytes with reduced size.


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	The early (A) trophozoites lie within red cells that do not change size or shape, at later development (B) they may remain unchanged or acquire subtle crenation.		The early (A) trophozoites lie within red cells that do not change size or shape, at later development (B) they may remain unchanged or acquire subtle crenation.


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	<gallery mode="nolines" widths="200px" heights="220px" >		<gallery mode="nolines" widths="200px" heights="220px" >
	File:~~MOETr~~.jpg\|link={{filepath:\|~~MOETr~~.jpg}}		File:3SizePMET.jpg\|A\|link={{filepath:\|3SizePMET.jpg}}
	File:~~MOITr~~.jpg\|link={{filepath:~~MOITr~~.jpg}}		File:4SizePFLT.jpg\|B\|link={{filepath:4SizePFLT.jpg}}
	</gallery>		</gallery>

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	<gallery mode="nolines" widths="200px" heights="220px" >		<gallery mode="nolines" widths="200px" heights="220px" >
	File:~~MMETr~~.jpg\|link={{filepath:\|~~MMETr~~.jpg}}		File:3SizePMET.jpg\|A\|link={{filepath:\|3SizePMET.jpg}}
	File:~~MMITr~~.jpg\|link={{filepath:~~MMITr~~.jpg}}		File:4SizePFLT.jpg\|B\|link={{filepath:4SizePFLT.jpg}}
	</gallery>		</gallery>


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Admin at 19:39, 24 March 2024

2024-03-24T19:39:56Z

← Older revision		Revision as of 21:39, 24 March 2024
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	'''RED CELLS WITH UNCHANGED SIZE AND SHAPE'''		'''RED CELLS WITH UNCHANGED SIZE AND SHAPE'''

	''P.~~faliparum~~''		''P.falciparum'' (and ''P.knowlesi'')

	Red cell size and shape is generally unchanged although they may become crenated		Red cell size and shape is generally unchanged although they may become crenated

Admin at 19:38, 24 March 2024

2024-03-24T19:38:54Z

← Older revision		Revision as of 21:38, 24 March 2024
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	'''ENLARGED AND DISTORTED RED CELLS'''		'''ENLARGED AND DISTORTED RED CELLS'''

			For both ''P.ovale'' and ''P.vivax'' the red cells become progressively enlarged and distorted as the parasites develop. It may not be possible to distingish the species based on red cell appearances, but there are differences which should be looked for.

	''P.ovale:''		''P.ovale:''

	~~The red cells in this species remain round and are often small in size~~

	<gallery mode="nolines" widths="200px" heights="220px" >		<gallery mode="nolines" widths="200px" heights="220px" >
	File:MOETr.jpg\|link={{filepath:\|MOETr.jpg}}		File:MOETr.jpg\|link={{filepath:\|MOETr.jpg}}
	File:MOITr.jpg\|link={{filepath:MOITr.jpg}}		File:MOITr.jpg\|link={{filepath:MOITr.jpg}}
	~~File:MOLTr.jpg\|link={{filepath:MOLTr.jpg}}~~
	</gallery>		</gallery>

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	~~'''~~ ''P.~~malariae'' '~~''		''P.vivax''

	<gallery mode="nolines" widths="200px" heights="220px" >		<gallery mode="nolines" widths="200px" heights="220px" >
	File:MMETr.jpg\|link={{filepath:\|MMETr.jpg}}		File:MMETr.jpg\|link={{filepath:\|MMETr.jpg}}
	File:MMITr.jpg\|link={{filepath:MMITr.jpg}}		File:MMITr.jpg\|link={{filepath:MMITr.jpg}}
	~~File:MMLTr.jpg\|link={{filepath:MMLTr.jpg}}~~
	</gallery>		</gallery>

	''The rings are small but generally appear more robust than ''P.falciparum'', the parasites become more solid often losing the central digestive vacuole and may become angular or extend as a band across the cells. Red cells are not enlarged or distorted and are often reduced in size as they mature in this species''
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	*
	* p..efalciparum red. cells unchanged in. size may. become crenated
	* p..eovale red. cells generally become enlarged and. ovoid may. become fimbriated
	* p..evivax red. cells significantly enlarged and. usually quite irregular

	~~these changes are. illustrated for. early and. late trophozoite below~~

	~~early trophozoites fsmall or normal p..emalariae round~~
	~~p..efalciparum round~~
	~~normal or. enlarged p..eovale may. become ovoid generally enlarged~~
	~~p..evivax may. become irregular late trophozoites file msi2.ejpg.~~


	~~species significance these changes can. be. very helpful in. identifying malaria species ---- '),~~

Admin at 19:30, 24 March 2024

2024-03-24T19:30:25Z

← Older revision		Revision as of 21:30, 24 March 2024
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	''' ''P.ovale'' ~~'''~~
			'''ENLARGED AND DISTORTED RED CELLS'''

			''P.ovale:''

			The red cells in this species remain round and are often small in size

	<gallery mode="nolines" widths="200px" heights="220px" >		<gallery mode="nolines" widths="200px" heights="220px" >