John: Created page with "
:'''Summary''' :CD57 is used in the identification and typing of LGL cells helping to differentiate between T- and LGL origin
:'''Background''' CD57 is a carbohydrate epitope expressed on the cell surface of T cells and peripheral NK cells where CD57 expression can be regarded as designating termi..."

2023-06-11T14:15:21Z

Created page with " <div style="background-color: #E0EEEE; {{round corners}} padding: 2em 2em; margin-right: 5px;"> :<span style="color:navy">'''Summary'''</span> :CD57 is used in the identification and typing of LGL cells helping to differentiate between T- and LGL origin </div> :<span style="color:navy">'''Background'''</span> CD57 is a carbohydrate epitope expressed on the cell surface of T cells and peripheral NK cells where CD57 expression can be regarded as designating termi..."

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<div style="background-color: #E0EEEE; {{round corners}} padding: 2em 2em; margin-right: 5px;">

:<span style="color:navy">'''Summary'''</span>

:CD57 is used in the identification and typing of LGL cells helping to differentiate between T- and LGL origin

</div>

:<span style="color:navy">'''Background'''</span>

CD57 is a carbohydrate epitope expressed on the cell surface of T cells and peripheral NK cells where CD57 expression can be regarded as designating terminal differentiation.

:<span style="color:navy">'''Diagnostic Use'''</span>

*Normal NK cells will express CD57 during response to infection, but expression may be absent or reduced in neoplastic NK cells.
*normal T-LGLs will generally express CD57 and expression in most often retained in T-LGL leukemia, however in common with most T cell antigens expression may be variable and sometimes absent

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CD57 - Revision history