''Plasmodium falciparum'': Morphology - Revision history

Admin at 10:43, 14 March 2024

2024-03-14T10:43:26Z

← Older revision		Revision as of 12:43, 14 March 2024
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	*Affected red cells have [[Size and shape of infected red cells\|normal size]] and haemoglobin content		*Affected red cells have [[Size and shape of infected red cells\|normal size]] and haemoglobin content

	[[''P.falciparum~~'' morphology of~~ early trophozoites\|Visit gallery of forms]]
			[[P.falciparum early trophozoites gallery\|Visit gallery of forms]]

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Admin at 10:42, 14 March 2024

2024-03-14T10:42:33Z

← Older revision		Revision as of 12:42, 14 March 2024
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	*Affected red cells have [[Size and shape of infected red cells\|normal size]] and haemoglobin content		*Affected red cells have [[Size and shape of infected red cells\|normal size]] and haemoglobin content

			[[''P.falciparum'' morphology of early trophozoites\|Visit gallery of forms]]

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Admin at 09:01, 13 March 2024

2024-03-13T09:01:59Z

← Older revision		Revision as of 11:01, 13 March 2024
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	The earliest developing stage:		The earliest developing stage, and often the only form present in this species:

	*[[Ring forms]] that are fine and delicate		*[[Ring forms]] that are fine and delicate

Admin at 17:39, 12 March 2024

2024-03-12T17:39:08Z

← Older revision		Revision as of 19:39, 12 March 2024
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	<gallery mode="nolines" widths=200px heights=200px>		<gallery mode="nolines" widths=200px heights=200px>
	File:PFETc.jpg\|link={{filepath:PFETc.jpg}}		File:PFETc.jpg\|link={{filepath:PFETc.jpg}}
			File:PFET-main image.jpg\|link={{filepath:PFET-main_image.jpg}}
	</gallery>		</gallery>
	<br clear=all>		<br clear=all>

Admin at 17:36, 12 March 2024

2024-03-12T17:36:55Z

← Older revision		Revision as of 19:36, 12 March 2024
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	'''The early trophozoite'''		'''The early trophozoite'''
	<gallery mode="nolines" widths=~~150px~~ heights=~~150px~~>		<gallery mode="nolines" widths=200px heights=200px>
	File:PFETc.jpg~~\|left~~\|link={{filepath:PFETc.jpg}}		File:PFETc.jpg\|link={{filepath:PFETc.jpg}}
	</gallery>		</gallery>
	<br clear=all>		<br clear=all>

Admin at 17:36, 12 March 2024

2024-03-12T17:36:26Z

← Older revision		Revision as of 19:36, 12 March 2024
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	'''The early trophozoite'''		'''The early trophozoite'''
	[[File:PFETc.jpg\|left~~\|220px~~\|link={{filepath:~~PFET~~.jpg}}]]		<gallery mode="nolines" widths=150px heights=150px>
			File:PFETc.jpg\|left\|link={{filepath:PFETc.jpg}}
			</gallery>
	<br clear=all>		<br clear=all>

Admin at 15:18, 8 March 2024

2024-03-08T15:18:45Z

← Older revision		Revision as of 17:18, 8 March 2024
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	'''The early trophozoite'''		'''The early trophozoite'''
	[[File:~~PFET~~.jpg\|left\|220px\|link={{filepath:PFET.jpg}}]]		[[File:PFETc.jpg\|left\|220px\|link={{filepath:PFET.jpg}}]]
	<br clear=all>		<br clear=all>

John: Created page with " ---- '''Geographical distribution''' ''P.falciparum'' infection occurs in tropical and subtropical areas of central and South America, Africa, and S.E.Asia; this resembles the distribution of ''P.malariae'' and overlaps but is distinct from the distribution of ''P.vivax'' and ''P.ovale''. Detailed geographical information may be accessed here: [https://malariaatlas.org/explorer/#/]. ---- '''The early trophozoite''' File:PFET.jpg|left|220px|link={{filepath:PFE..."

2024-02-26T11:54:37Z

Created page with " ---- '''Geographical distribution''' ''P.falciparum'' infection occurs in tropical and subtropical areas of central and South America, Africa, and S.E.Asia; this resembles the distribution of ''P.malariae'' and overlaps but is distinct from the distribution of ''P.vivax'' and ''P.ovale''. Detailed geographical information may be accessed here: [https://malariaatlas.org/explorer/#/]. ---- '''The early trophozoite''' File:PFET.jpg|left|220px|link={{filepath:PFE..."

New page

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'''Geographical distribution'''

''P.falciparum'' infection occurs in tropical and subtropical areas of central and South America, Africa, and S.E.Asia; this resembles the distribution of ''P.malariae'' and overlaps but is distinct from the distribution of ''P.vivax'' and ''P.ovale''.

Detailed geographical information may be accessed here: [https://malariaatlas.org/explorer/#/].

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'''The early trophozoite'''
[[File:PFET.jpg|left|220px|link={{filepath:PFET.jpg}}]]
 

The earliest developing stage:

*[[Ring forms]] that are fine and delicate
*Frequently the red cells contain [[multiple parasites]]
*Parasites may have a distinctive [[Double chromatin dot forms|double chromatin dot]] (signet ring form)
*Parasites may appear on the [[Accolé form|edge of the red cell]] and have a flattened appearance (accolé forms)
*Affected red cells have [[Size and shape of infected red cells|normal size]] and haemoglobin content

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'''The late trophozoite'''
 
[[File:PFLT.jpg|rleft|220px|link={{filepath:PFLT.jpg}}]]
 

The later developing stage:

*Parasites resemble early ring forms, but thicker and slightly larger
*Additional dots and clefts in cytoplasm when stained correctly (blue and relatively low in number).
*These are [[Maurer's dots and clefts]]
*[[Red cell size|Size and shape of infected red cells]] usually unaffected, but may become [[Red cell crenation|crenated]]
*Look for [[Double chromatin dot forms|double chromatin dot]], [[Accolé form| Accolé forms]], [[multiple parasites|multiple parasites/cell]]

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'''The schizont'''
[[File:PFS.jpg|left|220px|link={{filepath:PFS.jpg}}]]
 

The asexual replication stage:

*'''Do not generally circulate in this species unless overwhelming infection'''
*Contain multiple [[Schizonts|asexually formed]] developing parasites (most frequently 8-16)
*[[Schizonts|Development is progressive]]: first there are multiple chromatin dots, later a distinct nucleus and cytoplasm appears
*Loose [[Malaria pigment|pigment]] may be seen in clumps between the parasites
*Red cell size is generally unaffected but haemoglobin will largely be absent (metabolised by the parasites)

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'''The gametocyte'''

[[File:PFG1.jpg|left|220px|link={{filepath:PFG1.jpg}}]]
 

The sexual replication stage (very distinctive).

*Gametocytes are elongated but are also restricted by the red cell membrane
*They appear as [[Macrogametocytes & Microgametocytes|straight rods]] but frequently curve into a “[[Banana gametocyte|banana form]]”
*The residual membrane (empty of haemoglobin) may appear as a "blister" to the side of the parasite
*The single chromatin area is in the centre of the parasite, often [[Malaria pigment|pigment]] overlies or surrounds it
*Gametocytes may not be seen in many cases.

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'''Gallery'''

[[PLASMODIUM FALCIPARUM Gallery|Click here to see gallery of ''Plasmodium falciparum'' forms]]

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