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Storage changes in malaria

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How does schizont appearance change during their development?


If collected blood is not immediately prepared into a blood film the parasites may continue to develop.

In the initial stage this simply may involve ring forms thickening and becoming less easy to assign to a species. Later however, the lower pH and lower temperature of stored blood may begin to resemble changes normally encountered in the mosquito stomach, this may cause the male gametocyte to develop and release the male sexual forms "microgametes" that are normally formed in the mosquito stomach as part of sexual replication. These forms may be detected in blood and can be a source of confusion unless you are familiar with them.