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Revision as of 12:24, 24 March 2024


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Why is there an optimal pH for malaria evaluation?


The earliest stage following red cell invasion has a typical ting form:


Description


The best detection and species identification in malaria is made when staining is performed at a slightly more alkaline pH - this makes parasites more visible compared with the grey of the surrounding red cells and makes some structures such as cytoplasmic dots more visible. These features are detectable at standard staining pH and both detection and species identification can be performed, it is just less easy.