Species Identification: Difference between revisions
From haematologyetc.co.uk
No edit summary |
No edit summary |
||
Line 7: | Line 7: | ||
---- | ---- | ||
<div style="width: 100%"> | |||
{| class="wikitable" style="border-style: solid; border-width: 5px; color:black" | |||
|colspan="1" style = "font-size:90%; color:black; background: #bcd4e6"|'''1. The immunophenotype of the blast cells should be consistent with their "primitive" nature''' | |||
|} | |||
</div> | |||
'''''Plasmodium falciparum''''' | '''''Plasmodium falciparum''''' | ||
[[File:PFcombi.jpg|right|400px|link={{filepath:PFcombi.jpg}}]] | [[File:PFcombi.jpg|right|400px|link={{filepath:PFcombi.jpg}}]] |
Revision as of 17:58, 21 February 2024
1. The immunophenotype of the blast cells should be consistent with their "primitive" nature |
Plasmodium falciparum
Brief Summary
- Small and fine ring forms may have accole’ forms or multiple parastes/cell
- Maurer's dots and clefts are seen in late trophozoites
- Schizonts very rarely seen in blood unless severe infection
- Characteristic elongated (often curved) 'banana' gametocyes may be seen
For more information
- click for full description of P.falciparum mophology
- click to visit the gallery of P.falciparum forms
Plasmodium vivax
Brief summary
- Large and robust rings that become amoeboid during later development
- Red cells become increasingly enlarged and distorted as parasites mature
- Schüffner's dots are visible in appropriately stained thin blood films
- All forms tend to circulate with large schizont and gametocyte forms present
For more information
Plasmodium ovale
Brief summary
- rings are large and robust, with ring appearance often retained in late trophozoite stage
- Red cells are enlarged often with oval shape and may have characteristic fimbriation
- Schüffner's (James) dots seen in appropriately stained samples
- All forms tend to circulate, parasites are large but tend to be smaller than for P.vivax
For more information
Plasmodium malariae
Brief summary
- Small rings (less delicate than P.falciparum) and becoming elongated or solid as parasites mature
- Red cells often small remaining a round shape and with no added dots unless heavily stained
- All forms tend to circulate, characteristically look for "daisy" schizonts and small round gametocytes
- Parasite number is often low
For more information
Plasmodium knowlesi
Brief Summary
- Very limited geographical distribution within S.E Asia
- Small fine ring forms resemble those of P.falciparum
- Later rings are more solid or elongated similar to P.malariae
- Faint dots (Sinton or Mulligan's stippling) appear at later stages
- Schizonts & gametocytes resemble P.malariae but are less "neat"
- Characteristically red cell size is unaffected, although distortion may be seen
For more information