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...sed in the cytoplasm becoming expressed on as they mature. As an essential TCR component it is expressed almost exclusively by mature T cells. ...al Killer cell lymphoproliferative disorders do not express a conventional TCR so CD3 is not expressed.

...ound 95% express of circulating T cells express αβ chains and only 5% have gamma γδ. In tissues this can be different since the γδ T cells are more abun ...indicate a clonal proliferation most commonly will be hepatosplenic gamma-delta T-cell lymphoma or primary cutaneous t cell lymphoma (PTCL)