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  • 20:32, 11 May 2023 John talk contribs created page CD4 & CD8 (Created page with " <div style="background-color: #E0EEEE; {{round corners}} padding: 2em 2em; margin-right: 5px;"> :'''Systemic disease:''' On T lymphocytes these two co-stimulatory molecules define different functional types; an altered ratio between CD4 and CD8 cells can indicate systemic disease or immune dysfunction :'''Neoplasia:''' Expanded populations of CD4 or CD8 cells (or T cells with unusual expression patterns of these molecules) may represent a malignant clone, and the CD4...")