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Difference between revisions of "Platelet satellitism"

From www.haematologyetc.co.uk

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There is no definite causal association with any disease, but if severe the rosetted platelets may not be recorded by automated counters resulting in a pseudo-thrombocytopenia. Confirmation of a relationship of agglutination with EDTA can be accomplished by viewing a smear from capillary blood or with other anticoagulants.
 
There is no definite causal association with any disease, but if severe the rosetted platelets may not be recorded by automated counters resulting in a pseudo-thrombocytopenia. Confirmation of a relationship of agglutination with EDTA can be accomplished by viewing a smear from capillary blood or with other anticoagulants.
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Revision as of 16:34, 9 November 2019


Appearance:


Platelets adhering to neutrophils – on (the flattened) blood smear they surround the edge of the cell giving a “rosette” appearance



250px



Cause:


Platelet satellitism is an uncommon phenomenon that occurs in samples prepared with EDTA anticoagulation, it is believed to be a complex process involving antibody and EDTA-related protein changes

Described by:


Field and Macleod (1963)


Significance:


There is no definite causal association with any disease, but if severe the rosetted platelets may not be recorded by automated counters resulting in a pseudo-thrombocytopenia. Confirmation of a relationship of agglutination with EDTA can be accomplished by viewing a smear from capillary blood or with other anticoagulants.