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Difference between revisions of "Platelet satellitism"

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Revision as of 16:32, 9 November 2019


Appearance:


Platelets adhering to neutrophils – on (the flattened) blood smear they surround the edge of the cell giving a “rosette” appearance





Cause:


Platelet satellitism is an uncommon phenomenon that occurs in samples prepared with EDTA anticoagulation, it is believed to be a complex process involving antibody and EDTA-related protein changes

Described by:


Field and Macleod (1963)


Significance:


There is no definite causal association with any disease, but if severe the rosetted platelets may not be recorded by automated counters resulting in a pseudo-thrombocytopenia. Confirmation of a relationship of agglutination with EDTA can be accomplished by viewing a smear from capillary blood or with other anticoagulants.