Difference between revisions of "Phagocytosis of bacteria"
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Appearance: Recognisable microbes within the cytoplasm (usually within vacuoles) of neutrophils.
Neutrophils infected by bacteria: The first image pair (images 1a and 1b) show neutrophils containing diplococci of meningococcus – the paired organisms are present within vacuoles of the neutrophil. The second image pair shows streptococci – seen within the neutrophil (images 2a and 2b) but also outside the cell (image 2a).
Pathology: Each neutrophil can kill many microbes. Generally this occurs within tissues, but when this takes place in blood the phagocytosis can be observed with bacteria visible within neutrophils.
Note also: The relationship between neutrophil and microorganism is complex.
Some organisms (predominantly intracellular pathogens) can extend the neutrophil lifespan by disrupting the normal process of spontaneous apoptosis Others such as streptococci can promote rapid cell lysis or accelerate apoptosis of neutrophils