CD5: Difference between revisions
From haematologyetc.co.uk
(Created page with " <div style="background-color: #E0EEEE; {{round corners}} padding: 2em 2em; margin-right: 5px;"> :<span style="color:navy">'''Summary'''</span> :'''For mature B cell neoplasms''': CD5 is used to indicate likely CLL or MCL. However, expression is present on a subset of normal B cells, and also less frequently on other lymphoma types. Full interpretation therefore requires consideration of clonality and other markers. :'''In acute lymphoblastic leukaemia''': CD5 is u...") |
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:<span style="color:navy">'''Summary'''</span> | :<span style="color:navy">'''Summary'''</span> | ||
: | :For mature B cell neoplasms: CD5 is used to indicate likely CLL or MCL. However, expression is present on a subset of normal B cells, and also less frequently on other lymphoma types. Full interpretation therefore requires consideration of clonality and other markers. | ||
: | :In acute lymphoblastic leukaemia: CD5 is useful to indicate T lineage, with (relatively) low levels of aberrant expression. | ||
Revision as of 17:10, 30 April 2023
- Summary
- For mature B cell neoplasms: CD5 is used to indicate likely CLL or MCL. However, expression is present on a subset of normal B cells, and also less frequently on other lymphoma types. Full interpretation therefore requires consideration of clonality and other markers.
- In acute lymphoblastic leukaemia: CD5 is useful to indicate T lineage, with (relatively) low levels of aberrant expression.
Normal expression and function
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Diagnostic role
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Other relevant information:
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SUMMARY TABLES