Acute leukaemia types
From haematologyetc.co.uk
Marker patterns in typical acute myeloid leukaemia | |||
---|---|---|---|
CD45 expression in AML | |||
Typically expression of CD45 is less intense than normal T or B cells, with many cases showing variable expression with a wide spread of CD45 intensity. | |||
Markers of pimitive cell type expected in AML | |||
Marker | Expectation | Comment | |
CD19 | Expression is expected, but less strong than normal B cells | ||
κ/λ | Expect weak restricted κ or λ or absent expression | ||
CD5 | Characteristic of CLL, usually less strong than on T cells |