Acute leukaemia types: Difference between revisions
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|colspan="1" style = "font-size:90%; color:black;" |'''CD34''' | |colspan="1" style = "font-size:90%; color:black;" |'''CD34''' | ||
|colspan="1" style = "background:#004466;"| | |colspan="1" style = "background:#004466;"| | ||
|colspan="1" style = "font-size:84%;"| | |colspan="1" style = "font-size:84%;"|Frequently expressed, most often in less differentiated forms of AML. Expression often less intense than in lymphoid leukaemias | ||
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|colspan="1" style = "width: 4%; font-size:90%; color:black;" |'''TdT''' | |colspan="1" style = "width: 4%; font-size:90%; color:black;" |'''TdT''' | ||
|colspan="1" style = "width: 8%; background:#00b8e6;"| | |colspan="1" style = "width: 8%; background:#00b8e6;"| | ||
|colspan="1" style = "font-size:80%;"| | |colspan="1" style = "font-size:80%;"|Expressed particularly in less differentiated forms of AML. Often on a sub-population of cells; expression usually less intense than in lymphoid leukaemias | ||
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|colspan="1" style = "font-size:90%; color:black;" |'''CD7''' | |colspan="1" style = "font-size:90%; color:black;" |'''CD7''' |
Revision as of 12:14, 17 July 2023
Marker patterns in typical acute myeloid leukaemia | |||
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CD45 expression in AML | |||
Typically expression of CD45 is less intense than normal T or B cells, with many cases showing variable expression with a wide spread of CD45 intensity. | |||
Markers of pimitive cell type expected in AML | |||
Marker | Expectation | Comment | |
CD34 | Frequently expressed, most often in less differentiated forms of AML. Expression often less intense than in lymphoid leukaemias | ||
TdT | Expressed particularly in less differentiated forms of AML. Often on a sub-population of cells; expression usually less intense than in lymphoid leukaemias | ||
CD7 | Characteristic of CLL, usually less strong than on T cells |